CARD11 Antibody | EMD Millipore 06-1061 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CARD11 Antibody

catalog :

06-1061

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dog, chicken, cow

application :

western blot

product information

Catalog Number :

06-1061

Subcategory :

Inflammation & Immunology

Product Name :

Anti-CARD11 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q9BXL7

Host Name :

Rabbit

Antigen :

CARD11

Conjugate :

Affinity Purified

Product Description :

Anti-CARD11 Antibody

Cross Reactivity :

Human;Mouse;Rat;Horse;Canine

Background :

CARD11 is part of a group of CARD containing proteins, or proteins that contain caspase recruitment domain, belonging to the membrane-associated guanylate kinase (MAGUK) family functioning as molecular scaffolds at specialized locations of the plasma membrane for the production of multiprotein complexes. The CARD domain is a module for protein-binding that helps to regulate the production of CARD-containing proteins into complexes that signal NF-κB. CARD11 is a multidomain adaptor that is necessary for T-cell receptor (TCR) signaling activation of NF-κB as a necessary component of T-cell activation during adaptive immune response. In this pathway, CARD11 undergoes phosphorylation between its PDZ and coiled-coil domains by protein kinase D (PKC) on serine residues 564, 577, and 657 in order to activate NF-κB. Along with immunity, NF-κB is a critical component in the gene activation for pathways such as inflammation and apoptosis.

ALT Names :

caspase recruitment domain family, member 11;card-maguk protein 1;Carma 1;bcl10-interacting maguk protein 3;CARD-containing MAGUK protein 3

Immunogen :

KLH-conjugated linear peptide corresponding to the internal domain of human CARD11.

Specificity :

This antibody recognizes the internal domain of CARD11.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt