IRF4 Antibody, NT | EMD Millipore 06-1047 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

IRF4 Antibody, NT

catalog :

06-1047

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry

product information

Catalog Number :

06-1047

Subcategory :

Inflammation & Immunology

Product Name :

Anti-IRF4 Antibody, NT

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q15306

Host Name :

Rabbit

Antigen :

IRF4

Conjugate :

Affinity Purified

Product Description :

Anti-IRF4 Antibody, NT

Cross Reactivity :

Human;Mouse;Horse;Rat

Background :

Interferon regulatory factor 4, also known as IRF4, belongs to the IRF family. IRF4 encodes a 450 amino acid polypeptide with a predicted molecular weight of 51.6 kDa (Grossman 1996). The IRF4 gene is expressed in the spleen, lymphocytes and melanocytes, and is induced in to T cells after cross linking with the T cell receptor. IRF4 is a transcriptional activator that binds to the interferon stimulated response element (ISRE) of the MHC class I promoter. IRF4 is essential for mature T and B lymphocyte function. IRF4 interacts with MYD88 to prevent the interaction of IRF5, resulting in negative regulation of Toll Like Receptor (TLR) signaling. High levels of IRF4 have been associated with Epstein Barr Virus (EBV) and may be critical to EBV transformation. Further oncogenic potential has been associated with the involvement of IRF4 with hair color and pigmentation of the skin, which may cause multiple myeloma.

ALT Names :

Lymphocyte-specific interferon regulatory factor;Multiple myeloma oncogene ;interferon regulatory factor 4

Immunogen :

KLH conjugated linear peptide corresponding to the N-terminal region of IRF4.

Specificity :

This antibody recognizes the N-terminal region of IRF4 at and around amino acids 177-194.

Package Size :

100 µg

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at 2-8ºC from date of receipt.