MAVS/Cardif Antibody, NT | EMD Millipore 06-1043 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MAVS/Cardif Antibody, NT

catalog :

06-1043

quantity :

100 µL

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, chimpanzee

application :

western blot, immunoprecipitation

product information

Catalog Number :

06-1043

Subcategory :

Inflammation & Immunology

Product Name :

Anti-MAVS/Cardif Antibody, NT

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q7Z434

Host Name :

Rabbit

Antigen :

MAVS/Cardif

Conjugate :

Affinity Purified

Product Description :

Anti-MAVS/Cardif Antibody, NT

Cross Reactivity :

Human

Background :

Mitochondrial antiviral-signaling protein (MAVS) is thought to activate NF-KappaB and IRF 3, which increase antiviral immunity. This result seems to point to mitochondrial involvement in innate immunity, specifically during viral infection. MAVS also seems to be involved in the activation of interferons, but only during viral contamination. It has been shown that MAVS works in conjunction with retinoic acid inducible gene I (RIG-I) to identify and remove replicating viral genomes. MAVS has been shown to be cleaved during apoptosis and viral infection, which could mean that this is an essential step of infection.

ALT Names :

mitochondrial antiviral signaling protein;IFN-B promoter stimulator 1;CARD adaptor inducing IFN-beta;virus-induced signaling adapter variant 1b;Cardif;Interferon beta promoter stimulator protein 1;CARD adapter inducing interferon-beta;Putative NF-kappa-B-activating protein 031N;interferon-beta promoter stimulator protein 1;Virus-induced-signaling adapter;mitochondrial antiviral-signaling protein;CARD adapter inducing interferon beta;virus-induced signaling adaptor variant 1a;CARDIF;mitochondrial anti-viral signaling protein

Immunogen :

GST-tagged recombinant protein corresponding to the N-terminus of Mitochondrial antiviral-signaling protein.

Specificity :

This antibody recognizes MAVS at the N-terminus. Splicing variants observed at ~33, 55, 60, and 65 kDa. (Lad, S., et al. (2008). Molecular Immunology 45:2277–2287.)

Package Size :

100 µL

Uses :

Western Blotting;Immunoprecipitation

Storage :

Stable for 1 year at 2-8°C from date of receipt