LAP2 Antibody | EMD Millipore 06-1002 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

LAP2 Antibody

catalog :

06-1002

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dogs

application :

western blot, immunocytochemistry

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse	Korfali N, Florens L, Schirmer E. Isolation, Proteomic Analysis, and Microscopy Confirmation of the Liver Nuclear Envelope Proteome. Methods Mol Biol. 2016;1411:3-44 pubmed publisher

product information

Catalog Number :

06-1002

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-LAP2 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P42167

Host Name :

Rabbit

Antigen :

LAP2

Conjugate :

Affinity Purified

Product Description :

Anti-LAP2 Antibody

Cross Reactivity :

Human;Canine;Mouse;Rat

Background :

The inner membrane of the nuclear envelope is connected to the nuclear lamina. The main components of the nuclear lamina are Type V intermediate filaments called lamins and lamin binding proteins including lamin B receptor, emerin, MANI, LAP1 (3 isoforms), and LAP2 (several isoforms). The lamins are divided into two groups: the constitutively expressed lamin B and the developmentaly regulated lamin A. The best characterized isoforms of lamin binding protein LAP2 are LAP2α and LAP2β. LAP2β is a type II membrane protein in the inner nuclear membrane that binds lamin B and is important to cell viability and controlling nuclear lamina growth. LAP2α has been characterized as a nucleoplasmic protein that interacts with A-type lamins to control gene expression, transcription, and chromatin organization.

ALT Names :

LEM domain containing 4;TP alpha;TP beta/gamma;TPRP isoform alpha;TPRP isoforms beta/gamma ;Thymopoietin isoform alpha;Thymopoietin, isoforms beta/gamma;Thymopoietin-related peptide isoform alpha;Thymopoietin-related peptide isoforms beta/gamma;lamina-associated polypeptide 2

Immunogen :

KLH-conjugated synthetic linear peptide corresponding to LAP2.

Specificity :

This antibody recognizes LAP2.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry;Immunofluorescence

Storage :

Stable for 1 year at 2-8ºC from date of receipt.