phospho-STAT5A/B (Tyr694/699) Antibody, clone A11W, rabbit monoclonal

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho-STAT5A/B (Tyr694/699) Antibody, clone A11W, rabbit monoclonal

catalog :

05-886

quantity :

100 µL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

A11W

reactivity :

human, mouse, bovine, chimpanzee

application :

western blot

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; human; tbl s3	Cheng H, Liang Y, Kuo Y, Chuu C, Lin C, Lee M, et al. Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data. Cell Death Dis. 2015;6:e1753 pubmed publisher
western blot; human	Caldarelli A, Muller J, Paskowski Rogacz M, Herrmann K, Bauer R, Koch S, et al. A genome-wide RNAi screen identifies proteins modulating aberrant FLT3-ITD signaling. Leukemia. 2013;27:2301-10 pubmed publisher
	Wiemer M, Osiewacz H. The proteasome activity reporter GFP-Cl1 is degraded by autophagy in the aging model Podospora anserina. F1000Res. 2014;3:230 pubmed publisher
	Lellis Santos C, Sakamoto L, Bromati C, Nogueira T, Leite A, Yamanaka T, et al. The regulation of Rasd1 expression by glucocorticoids and prolactin controls peripartum maternal insulin secretion. Endocrinology. 2012;153:3668-78 pubmed publisher
	Ochsner S, Strick Marchand H, Qiu Q, Venable S, Dean A, Wilde M, et al. Transcriptional profiling of bipotential embryonic liver cells to identify liver progenitor cell surface markers. Stem Cells. 2007;25:2476-87 pubmed

product information

Catalog Number :

05-886

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone A11W, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P42229;P51692

Host Name :

Rabbit

Antigen :

phospho-STAT5A/B (Tyr694/699)

Clone :

A11W

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone A11W, rabbit monoclonal

Cross Reactivity :

Human;Mouse

Background :

The STAT proteins (signal transducer and activator of transcription) comprise a family of transcription factors. STATs are activated through tyrosine phosphorylation, mainly by JAK kinases, which results in their dimerization, nuclear translocation and regulation of gene expression. STAT5 activity is induced by numerous cytokines and growth factors. While STAT5A and STAT5B share 96% amino acid homology, the two isoforms have distinct physiological functions. Phosphorylation of tyrosine 694/699 is a key marker of STAT5A/B activation.

Immunogen :

KLH-conjugated, synthetic peptide containing the sequence DG p YVK in which p Y corresponds to phospho-tyrosine at residue 694 of human STAT5A or residue 699 of STAT5B.

Specificity :

phospho-STAT5A/B (Tyr694/699)

Package Size :

100 µL

Uses :

Western Blotting

Storage :

stable 2 years at -20°C from date of shipment