This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Histone H4 Antibody, pan, clone 62-10C-2, rabbit monoclonal
catalog :
05-858R
quantity :
100 μL
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
62-10C-2
reactivity :
human, mouse
application :
western blot
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2000; fig s13
Karuppagounder S, Alim I, Khim S, Bourassa M, Sleiman S, John R, et al. Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models. Sci Transl Med. 2016;8:328ra29 pubmed publisher
  • western blot; mouse; fig 3c
Sleiman S, Olson D, Bourassa M, Karuppagounder S, Zhang Y, Gale J, et al. Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of HDAC inhibition. J Neurosci. 2014;34:14328-37 pubmed publisher
  • western blot; human
Lauffer B, Mintzer R, Fong R, Mukund S, Tam C, Zilberleyb I, et al. Histone deacetylase (HDAC) inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability. J Biol Chem. 2013;288:26926-43 pubmed publisher
Zoeller E, PEDRO B, Konen J, Dwivedi B, Rupji M, Sundararaman N, et al. Genetic heterogeneity within collective invasion packs drives leader and follower cell phenotypes. J Cell Sci. 2019;132: pubmed publisher
Guha M, Srinivasan S, Johnson F, Ruthel G, Guja K, Garcia Diaz M, et al. hnRNPA2 mediated acetylation reduces telomere length in response to mitochondrial dysfunction. PLoS ONE. 2018;13:e0206897 pubmed publisher
product information
Catalog Number :
05-858R
Subcategory :
Epigenetics & Nuclear Function
Product Name :
Anti-Histone H4 Antibody, pan, clone 62-10C-2, rabbit monoclonal
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P62805
Host Name :
Rabbit
Antigen :
Histone H4
Clone :
62-10C-2
Conjugate :
Purified
Isotype :
IgG
Product Description :
Anti-Histone H4 Antibody, pan, clone 62-10C-2, rabbit monoclonal
Cross Reactivity :
Human
Background :
Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the 'beads on a string' structure.
ALT Names :
H4;Histone H4;H4 histone family, member A;histone 1, H4a;histone cluster 1, H4a
Immunogen :
KLH-conjugated, synthetic peptide corresponding to amino acids 17-28 of Histone H4.
Specificity :
This antibody recognizes histone H4.
Package Size :
100 μL
Uses :
Western Blotting
Storage :
Stable for 1 year at -20°C from date of receipt.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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