Cyclin D1 Antibody | EMD Millipore 05-815 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Cyclin D1 Antibody

catalog :

05-815

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 4

Reference
Shaposhnikov D, Kuffer C, Storchova Z, Posern G. Myocardin related transcription factors are required for coordinated cell cycle progression. Cell Cycle. 2013;12:1762-72 pubmed publisher
Joly S, Pernet V, Samardzija M, Grimm C. Pax6-positive Müller glia cells express cell cycle markers but do not proliferate after photoreceptor injury in the mouse retina. Glia. 2011;59:1033-46 pubmed publisher
Yue J, Wei W, Lam C, Zhao Y, Dong M, Zhang L, et al. CD38/cADPR/Ca2+ pathway promotes cell proliferation and delays nerve growth factor-induced differentiation in PC12 cells. J Biol Chem. 2009;284:29335-42 pubmed publisher
Nomiyama T, Zhao Y, Gizard F, Findeisen H, Heywood E, Jones K, et al. Deficiency of the NR4A neuron-derived orphan receptor-1 attenuates neointima formation after vascular injury. Circulation. 2009;119:577-86 pubmed publisher

product information

Catalog Number :

05-815

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Cyclin D1 Antibody

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P24385

Host Name :

Mouse

Antigen :

Cyclin D1

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Cyclin D1 Antibody

Cross Reactivity :

Mouse;Rat

Background :

Progression through G1 phase and transition from G1 to S phase of the cell division cycle is controlled by activation of a distinct series of serine/threonine kinase complexes which comprise of a cyclin regulatory subunit and a cyclin dependent kinase (cdk). D type cyclins are induced earlier than cyclin E in G1 and can form complexes with cdk2,-4,-5, and -6. Cyclin D1 is a nuclear protein during G1 phase and disappears from the nucleus in S-phase. Among the key cell cycle regulators, cyclin D1 has been implicated most strongly as a proto-oncogene in several human tumor types, including breast carcinomas.

Immunogen :

GST fusion protein cleaved with Factor Xa and gel purified, corresponding to complete mouse Cyclin D1

Specificity :

Cyclin D1

Package Size :

100 µg

Uses :

Immunoprecipitation;Western Blotting;Immunocytochemistry

Storage :

Stable for 2 years at -20°C