HDAC3 Antibody, clone 3G6 | EMD Millipore 05-813 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

HDAC3 Antibody, clone 3G6

catalog :

05-813

quantity :

200 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3G6

The same clone is also sold as:

Abcam: ab187945

reactivity :

chicken

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 1

Reference
Demmerle J, Koch A, Holaska J. The nuclear envelope protein emerin binds directly to histone deacetylase 3 (HDAC3) and activates HDAC3 activity. J Biol Chem. 2012;287:22080-8 pubmed publisher

product information

Catalog Number :

05-813

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-HDAC3 Antibody, clone 3G6

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O15379

Host Name :

Mouse

Antigen :

HDAC3

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-HDAC3 Antibody, clone 3G6

Cross Reactivity :

Bovine;Human;Hamster;Mouse

Background :

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. HDAC3 is regarded as a potential tumor suppressor gene.

Immunogen :

peptide (NEFYDGDHDNDKESDVEI) corresponding to amino acids 411-428 of human HDAC3

Specificity :

HDAC3

Package Size :

200 µg

Uses :

Immunoprecipitation;Western Blotting;Immunocytochemistry

Storage :

2 years at -20°C