p70 S6 Kinase Antibody, clone 20-10C-6, rabbit monoclonal | EMD Millipore 05-781R product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

p70 S6 Kinase Antibody, clone 20-10C-6, rabbit monoclonal

catalog :

05-781R

quantity :

100 µL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

20-10C-6

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 2c	Vergani E, Di Guardo L, Dugo M, Rigoletto S, Tragni G, Ruggeri R, et al. Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b. Oncotarget. 2016;7:4428-41 pubmed publisher
western blot; human	Ramírez Peinado S, León Annicchiarico C, Galindo Moreno J, Iurlaro R, Caro Maldonado A, Prehn J, et al. Glucose-starved cells do not engage in prosurvival autophagy. J Biol Chem. 2013;288:30387-98 pubmed publisher
	Zhang H, Cui Z, Luo G, Zhang J, Ma T, Hu N, et al. Ghrelin attenuates intestinal ischemia/reperfusion injury in mice by activating the mTOR signaling pathway. Int J Mol Med. 2013;32:851-9 pubmed publisher

product information

Catalog Number :

05-781R

Subcategory :

Cell Signaling

Product Name :

Anti-p70 S6 Kinase Antibody, clone 20-10C-6, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P23443

Host Name :

Rabbit

Antigen :

p70 S6 Kinase

Clone :

20-10C-6

Conjugate :

Unconjugated

Isotype :

IgG

Product Description :

Anti-p70 S6 Kinase Antibody, clone 20-10C-6, rabbit monoclonal

Cross Reactivity :

Human;Mouse;Rat

Background :

S6 Kinase is a Ser/Thr kinase which phosphorylates the 40S ribosomal protein S6, and several translation-regulatory factors. S6 kinase is activated by phosphorylation of multiple sites by mTOR. S6K is an important regulator of protein synthesis, along with MAP Kinase. In neurons, S6K is linked to the cytoskeleton by neurabin, which may play a role in its activation. Rsk3 (MAPKAP Kinase 1c) and Rsk4 are also known as the Ribosomal Protein S6 Kinase, 90 kDa, polypeptide 2 and 6, respectively.

ALT Names :

70 kDa ribosomal protein S6 kinase 1;Ribosomal protein S6 kinase I;p70 S6 kinase alpha;p70 S6 kinase, alpha 1;p70 S6 kinase, alpha 2;ribosomal protein S6 kinase, 70kD, polypeptide 1;ribosomal protein S6 kinase, 70kDa, polypeptide 1;serine/threonine kinase 14 alpha

Immunogen :

KLH-conjugated linear peptide corresponding to human p70 S6 Kinase at and around the N-terminus.

Specificity :

This antibody recognizes p70 S6 Kinase at the N-terminus.

Package Size :

100 µL

Uses :

Western Blotting;Immunoprecipitation;Immunocytochemistry

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.