Mps1 Antibody, NT, clone 3-472-1 | EMD Millipore 05-682 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Mps1 Antibody, NT, clone 3-472-1

catalog :

05-682

quantity :

200 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3-472-1

reactivity :

human, mouse

application :

western blot, immunocytochemistry, western blot knockout validation

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; fig 2	Diril M, Bisteau X, Kitagawa M, Caldez M, Wee S, Gunaratne J, et al. Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint. PLoS Genet. 2016;12:e1006310 pubmed publisher
western blot; human; loading ...; fig 1d	Chen X, Yu C, Gao J, Zhu H, Cui B, Zhang T, et al. A novel USP9X substrate TTK contributes to tumorigenesis in non-small-cell lung cancer. Theranostics. 2018;8:2348-2360 pubmed publisher
western blot; human; loading ...; fig s2b	Mason J, Wei X, Fletcher G, Kiarash R, Brokx R, Hodgson R, et al. Functional characterization of CFI-402257, a potent and selective Mps1/TTK kinase inhibitor, for the treatment of cancer. Proc Natl Acad Sci U S A. 2017;114:3127-3132 pubmed publisher
immunocytochemistry; human; loading ...; fig 4a western blot; human; loading ...; fig 4c	Zhang P, Zhang Y, Gao K, Wang Y, Jin X, Wei Y, et al. ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments. Oncotarget. 2015;6:41550-65 pubmed publisher
immunocytochemistry; human; fig 1	Gurden M, Westwood I, Faisal A, Naud S, Cheung K, McAndrew C, et al. Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. Cancer Res. 2015;75:3340-54 pubmed publisher
western blot; human	Kaistha B, Honstein T, Muller V, Bielak S, Sauer M, Kreider R, et al. Key role of dual specificity kinase TTK in proliferation and survival of pancreatic cancer cells. Br J Cancer. 2014;111:1780-7 pubmed publisher
immunocytochemistry; human; 1:100	Ballister E, Riegman M, Lampson M. Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint. J Cell Biol. 2014;204:901-8 pubmed publisher
	Janssen L, Averink T, Blomen V, Brummelkamp T, Medema R, Raaijmakers J. Loss of Kif18A Results in Spindle Assembly Checkpoint Activation at Microtubule-Attached Kinetochores. Curr Biol. 2018;28:2685-2696.e4 pubmed publisher
	Koch A, Maia A, Janssen A, Medema R. Molecular basis underlying resistance to Mps1/TTK inhibitors. Oncogene. 2016;35:2518-28 pubmed publisher

product information

Catalog Number :

05-682

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Mps1 Antibody, NT, clone 3-472-1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P33981

Host Name :

Mouse

Antigen :

Mps1

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-Mps1 Antibody, NT, clone 3-472-1

Cross Reactivity :

Human

Immunogen :

His-tagged fusion protein corresponding to amino acids 3-856 of human Mps1

Specificity :

Mps1

Package Size :

200 µg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt