| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:5000; loading ...; fig 2f
| Zhang Y, Shi J, Liu X, Feng L, Gong Z, Koppula P, et al. BAP1 links metabolic regulation of ferroptosis to tumour suppression. Nat Cell Biol. 2018;20:1181-1192 pubmed publisher |
- ChIP-Seq; mouse; loading ...; fig 3a
| Endoh M, Endo T, Shinga J, Hayashi K, Farcas A, Ma K, et al. PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes. elife. 2017;6: pubmed publisher |
- chromatin immunoprecipitation; human; loading ...; fig st3
| Gwak J, Shin J, Lee K, Hong S, Oh S, Goh S, et al. SFMBT2 (Scm-like with four mbt domains 2) negatively regulates cell migration and invasion in prostate cancer cells. Oncotarget. 2016;7:48250-48264 pubmed publisher |
- immunocytochemistry; rat; 1:100; fig 2
- western blot; rat; 1:1000; fig 2
| Mata Garrido J, Casafont I, Tapia O, Berciano M, Lafarga M. Neuronal accumulation of unrepaired DNA in a novel specific chromatin domain: structural, molecular and transcriptional characterization. Acta Neuropathol Commun. 2016;4:41 pubmed publisher |
- immunocytochemistry; human; fig 5
| Cristini A, Park J, Capranico G, Legube G, Favre G, Sordet O. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res. 2016;44:1161-78 pubmed publisher |
- western blot; mouse; fig 1a
| Yao X, Tang Z, Fu X, Yin J, Liang Y, Li C, et al. The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination. EMBO J. 2015;34:2885-902 pubmed publisher |
- chromatin immunoprecipitation; human; fig s10
| Ohashi M, Holthaus A, Calderwood M, Lai C, Krastins B, Sarracino D, et al. The EBNA3 family of Epstein-Barr virus nuclear proteins associates with the USP46/USP12 deubiquitination complexes to regulate lymphoblastoid cell line growth. PLoS Pathog. 2015;11:e1004822 pubmed publisher |
- chromatin immunoprecipitation; mouse
| Inagaki T, Iwasaki S, Matsumura Y, Kawamura T, Tanaka T, Abe Y, et al. The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis. J Biol Chem. 2015;290:4163-77 pubmed publisher |
- western blot; fruit fly ; 1:250
| Fereres S, Simón R, Mohd Sarip A, Verrijzer C, Busturia A. dRYBP counteracts chromatin-dependent activation and repression of transcription. PLoS ONE. 2014;9:e113255 pubmed publisher |
| Hock A, Vigneron A, Vousden K. Ubiquitin-specific peptidase 42 (USP42) functions to deubiquitylate histones and regulate transcriptional activity. J Biol Chem. 2014;289:34862-70 pubmed publisher |
| Putiri E, Tiedemann R, Liu C, Choi J, Robertson K. Impact of human MLL/COMPASS and polycomb complexes on the DNA methylome. Oncotarget. 2014;5:6338-52 pubmed |
- chromatin immunoprecipitation; human
- western blot; human; 1:500
| Cao Q, Wang X, Zhao M, Yang R, Malik R, Qiao Y, et al. The central role of EED in the orchestration of polycomb group complexes. Nat Commun. 2014;5:3127 pubmed publisher |
- chromatin immunoprecipitation; mouse
- chromatin immunoprecipitation; human
| Zhou J, Dhawan S, Fu H, Snyder E, Bottino R, Kundu S, et al. Combined modulation of polycomb and trithorax genes rejuvenates ? cell replication. J Clin Invest. 2013;123:4849-58 pubmed |
- immunocytochemistry; human
- western blot; human
| Sharma N, Zhu Q, Wani G, He J, Wang Q, Wani A. USP3 counteracts RNF168 via deubiquitinating H2A and ?H2AX at lysine 13 and 15. Cell Cycle. 2014;13:106-14 pubmed publisher |
| Yuan G, Ma B, Yuan W, Zhang Z, Chen P, Ding X, et al. Histone H2A ubiquitination inhibits the enzymatic activity of H3 lysine 36 methyltransferases. J Biol Chem. 2013;288:30832-42 pubmed publisher |
| Sy S, Jiang J, O W, Deng Y, Huen M. The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaks. Nucleic Acids Res. 2013;41:8572-80 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig s3j
| Modzelewski A, Holmes R, Hilz S, Grimson A, Cohen P. AGO4 regulates entry into meiosis and influences silencing of sex chromosomes in the male mouse germline. Dev Cell. 2012;23:251-64 pubmed publisher |
| Li X, Corsa C, Pan P, Wu L, Ferguson D, Yu X, et al. MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1. Mol Cell Biol. 2010;30:5335-47 pubmed publisher |
- immunocytochemistry; mouse; 1:100
| Takada Y, Isono K, Shinga J, Turner J, Kitamura H, Ohara O, et al. Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes. Development. 2007;134:579-90 pubmed |
| Róna G, Roberti D, Yin Y, Pagan J, Homer H, Sassani E, et al. PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A.Z loading. elife. 2018;7: pubmed publisher |
| Zhang Z, Jones A, Wu W, Kim J, Kang Y, Bi X, et al. Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing. Proc Natl Acad Sci U S A. 2017;114:E7949-E7958 pubmed publisher |
| Matveevsky S, Bakloushinskaya I, Kolomiets O. Unique sex chromosome systems in Ellobius: How do male XX chromosomes recombine and undergo pachytene chromatin inactivation?. Sci Rep. 2016;6:29949 pubmed publisher |
| Ohhata T, Matsumoto M, Leeb M, Shibata S, Sakai S, Kitagawa K, et al. Histone H3 Lysine 36 Trimethylation Is Established over the Xist Promoter by Antisense Tsix Transcription and Contributes to Repressing Xist Expression. Mol Cell Biol. 2015;35:3909-20 pubmed publisher |
| McFarland K, Das S, Sun T, Leyfer D, Kim M, Xia E, et al. Genome-wide increase in histone H2A ubiquitylation in a mouse model of Huntington's disease. J Huntingtons Dis. 2013;2:263-77 pubmed publisher |
| Shen H, Chen Z, Ding X, Qi X, Cen J, Wang Y, et al. BMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progression. J Cell Mol Med. 2014;18:1004-17 pubmed publisher |
| Mou L, Zhang Q, Wang Y, Zhang Q, Sun L, Li C, et al. Identification of Ube2b as a novel target of androgen receptor in mouse sertoli cells. Biol Reprod. 2013;89:32 pubmed publisher |
| Buchsbaum S, Bercovich B, Ziv T, Ciechanover A. Modification of the inflammatory mediator LRRFIP2 by the ubiquitin-like protein FAT10 inhibits its activity during cellular response to LPS. Biochem Biophys Res Commun. 2012;428:11-6 pubmed publisher |
| Noda A, Hirai Y, Hamasaki K, Mitani H, Nakamura N, Kodama Y. Unrepairable DNA double-strand breaks that are generated by ionising radiation determine the fate of normal human cells. J Cell Sci. 2012;125:5280-7 pubmed publisher |
| Endoh M, Endo T, Endoh T, Isono K, Sharif J, Ohara O, et al. Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity. PLoS Genet. 2012;8:e1002774 pubmed publisher |
| Oguro H, Yuan J, Tanaka S, Miyagi S, Mochizuki Kashio M, Ichikawa H, et al. Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes. J Exp Med. 2012;209:445-54 pubmed publisher |
| Lai Y, Song M, Hakala K, Weintraub S, Shiio Y. The interaction of the von Hippel-Lindau tumor suppressor and heterochromatin protein 1. Arch Biochem Biophys. 2012;518:103-10 pubmed publisher |
| Yu T, Chen X, Zhang W, Colon D, Shi J, Napier D, et al. Regulation of the potential marker for intestinal cells, Bmi1, by ?-catenin and the zinc finger protein KLF4: implications for colon cancer. J Biol Chem. 2012;287:3760-8 pubmed publisher |
| Mochizuki Kashio M, Mishima Y, Miyagi S, Negishi M, Saraya A, Konuma T, et al. Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells. Blood. 2011;118:6553-61 pubmed publisher |
| Dufourt J, Brasset E, Desset S, Pouchin P, Vaury C. Polycomb group-dependent, heterochromatin protein 1-independent, chromatin structures silence retrotransposons in somatic tissues outside ovaries. DNA Res. 2011;18:451-61 pubmed publisher |
| Ma M, Heath C, Hair A, West A. Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity. PLoS Genet. 2011;7:e1002175 pubmed publisher |
| Inagaki A, Sleddens Linkels E, Wassenaar E, Ooms M, van Cappellen W, Hoeijmakers J, et al. Meiotic functions of RAD18. J Cell Sci. 2011;124:2837-50 pubmed publisher |
| Lang G, Bonnet J, Umlauf D, Karmodiya K, Koffler J, Stierlé M, et al. The tightly controlled deubiquitination activity of the human SAGA complex differentially modifies distinct gene regulatory elements. Mol Cell Biol. 2011;31:3734-44 pubmed publisher |
| Krichevsky A, Zaltsman A, Lacroix B, Citovsky V. Involvement of KDM1C histone demethylase-OTLD1 otubain-like histone deubiquitinase complexes in plant gene repression. Proc Natl Acad Sci U S A. 2011;108:11157-62 pubmed publisher |
| Sinnar S, Small C, Evanoff R, Reinholdt L, Griswold M, Kopito R, et al. Altered testicular gene expression patterns in mice lacking the polyubiquitin gene Ubb. Mol Reprod Dev. 2011;78:415-25 pubmed publisher |
| Yuan J, Takeuchi M, Negishi M, Oguro H, Ichikawa H, Iwama A. Bmi1 is essential for leukemic reprogramming of myeloid progenitor cells. Leukemia. 2011;25:1335-43 pubmed publisher |
| Eskeland R, Freyer E, Leeb M, Wutz A, Bickmore W. Histone acetylation and the maintenance of chromatin compaction by Polycomb repressive complexes. Cold Spring Harb Symp Quant Biol. 2010;75:71-8 pubmed publisher |
| Baldeyron C, Soria G, Roche D, Cook A, Almouzni G. HP1alpha recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair. J Cell Biol. 2011;193:81-95 pubmed publisher |
| Joo H, Jones A, Yang C, Zhai L, Smith A, Zhang Z, et al. Regulation of histone H2A and H2B deubiquitination and Xenopus development by USP12 and USP46. J Biol Chem. 2011;286:7190-201 pubmed publisher |
| Chakravarthy H, Ormsbee B, Mallanna S, Rizzino A. Rapid activation of the bivalent gene Sox21 requires displacement of multiple layers of gene-silencing machinery. FASEB J. 2011;25:206-18 pubmed publisher |
| Negishi M, Saraya A, Mochizuki S, Helin K, Koseki H, Iwama A. A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1. PLoS ONE. 2010;5:e12373 pubmed publisher |
| Borchert G, Holton N, Edwards K, Vogel L, Larson E. Histone H2A and H2B are monoubiquitinated at AID-targeted loci. PLoS ONE. 2010;5:e11641 pubmed publisher |
| Feng L, Wang J, Chen J. The Lys63-specific deubiquitinating enzyme BRCC36 is regulated by two scaffold proteins localizing in different subcellular compartments. J Biol Chem. 2010;285:30982-8 pubmed publisher |
| Thakar A, Parvin J, Zlatanova J. BRCA1/BARD1 E3 ubiquitin ligase can modify histones H2A and H2B in the nucleosome particle. J Biomol Struct Dyn. 2010;27:399-406 pubmed |
| Baumann C, De La Fuente R. ATRX marks the inactive X chromosome (Xi) in somatic cells and during imprinted X chromosome inactivation in trophoblast stem cells. Chromosoma. 2009;118:209-22 pubmed publisher |
| Bergink S, Salomons F, Hoogstraten D, Groothuis T, de Waard H, Wu J, et al. DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A. Genes Dev. 2006;20:1343-52 pubmed |
