BrdU Antibody, clone BU-1 | EMD Millipore 05-633 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

BrdU Antibody, clone BU-1

catalog :

05-633

quantity :

4 vials

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

BU-1

application :

immunocytochemistry, immunohistochemistry - paraffin section

citations: 6

Reference
Di Pietro C, Marazziti D, La Sala G, Abbaszadeh Z, Golini E, Matteoni R, et al. Primary Cilia in the Murine Cerebellum and in Mutant Models of Medulloblastoma. Cell Mol Neurobiol. 2017;37:145-154 pubmed publisher
Gao X, Ma W, Nie J, Zhang C, Zhang J, Yao G, et al. A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation. Cell Death Dis. 2015;6:e1610 pubmed publisher
Tudor C, Bruns H, Daniel C, Distel L, Hartmann A, Gerbitz A, et al. Macrophages and dendritic cells as actors in the immune reaction of classical Hodgkin lymphoma. PLoS ONE. 2014;9:e114345 pubmed publisher
Dementyeva E, Shevchenko A, Anopriyenko O, Mazurok N, Elisaphenko E, Nesterova T, et al. Difference between random and imprinted X inactivation in common voles. Chromosoma. 2010;119:541-52 pubmed publisher
Distler U, Souady J, Hülsewig M, Drmić Hofman I, Haier J, Friedrich A, et al. Shiga toxin receptor Gb3Cer/CD77: tumor-association and promising therapeutic target in pancreas and colon cancer. PLoS ONE. 2009;4:e6813 pubmed publisher
Shevchenko A, Pavlova S, Dementyeva E, Zakian S. Mosaic heterochromatin of the inactive X chromosome in vole Microtus rossiaemeridionalis. Mamm Genome. 2009;20:644-53 pubmed publisher

product information

Catalog Number :

05-633

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-BrdU Antibody, clone BU-1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Mouse

Antigen :

BrdU

Conjugate :

Culture Supernatant

Isotype :

IgG2a

Product Description :

Anti-BrdU Antibody, clone BU-1

Cross Reactivity :

All

Background :

The immunocytochemical detection of bromodeoxyuridine (BrdU) incorporated into DNA is a powerful tool to study the cytokinetics of normal and neoplastic cells. In vitro or in vivo labeling of tumor cells with the thymidine analogue BrdU and the subsequent detection of incorporated BrdU with specific anti-BrdU monoclonal antibodies is an accurate and comprehensive method to quantitate the degree of DNA-synthesis. BrdU is incorporated into the newly synthezised DNA of the S-phase cells and can thus provide an estimate for the fraction of cells in S-phase. Also dynamic proliferative information (such as the S-phase transit rate and the potential doubling time) can be obtained, by means of bivariate BrdU/DNA flow cytometric analysis.

Immunogen :

5-iodouridine:ovalbumin conjugate

Specificity :

5-Bromo-2-deoxyuridine

Package Size :

4 vials

Uses :

Immunocytochemistry

Storage :

2 years at -20°C