phospho-Histone H3 (Ser10) Antibody, clone RR002 | EMD Millipore 05-598 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho-Histone H3 (Ser10) Antibody, clone RR002

catalog :

05-598

quantity :

200 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

RR002

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

citations: 12

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:400; loading ...; fig 9b	Alshehri B, Pagnin M, Lee J, Petratos S, Richardson S. The Role of Transthyretin in Oligodendrocyte Development. Sci Rep. 2020;10:4189 pubmed publisher
western blot; human; 1:5000; fig 1	Grandy R, Whitfield T, Wu H, Fitzgerald M, VanOudenhove J, Zaidi S, et al. Genome-Wide Studies Reveal that H3K4me3 Modification in Bivalent Genes Is Dynamically Regulated during the Pluripotent Cell Cycle and Stabilized upon Differentiation. Mol Cell Biol. 2016;36:615-27 pubmed publisher
western blot; mouse; 1:500	Chittoor V, Sooyeon L, Rangaraju S, Nicks J, Schmidt J, Madorsky I, et al. Biochemical characterization of protein quality control mechanisms during disease progression in the C22 mouse model of CMT1A. ASN Neuro. 2013;5:e00128 pubmed publisher
immunocytochemistry; human; 1:1000; fig 7	Imbalzano K, Cohet N, Wu Q, Underwood J, Imbalzano A, Nickerson J. Nuclear shape changes are induced by knockdown of the SWI/SNF ATPase BRG1 and are independent of cytoskeletal connections. PLoS ONE. 2013;8:e55628 pubmed publisher
	Golenberg N, Squirrell J, Bennin D, Rindy J, Pistono P, Eliceiri K, et al. Citrullination regulates wound responses and tissue regeneration in zebrafish. J Cell Biol. 2020;219: pubmed publisher
	Noguchi K, Hongama K, Hariki S, Nonomiya Y, Katayama K, Sugimoto Y. Functional Effects of AKT3 on Aurora Kinase Inhibitor-induced Aneuploidy. J Biol Chem. 2017;292:1910-1924 pubmed publisher
	Chen C, Ho H, Wu M, Layne M, Yet S. Modulation of cysteine-rich protein 2 expression in vascular injury and atherosclerosis. Mol Biol Rep. 2014;41:7033-41 pubmed publisher
	Lai F, Orom U, Cesaroni M, Beringer M, Taatjes D, Blobel G, et al. Activating RNAs associate with Mediator to enhance chromatin architecture and transcription. Nature. 2013;494:497-501 pubmed publisher
	Andorfer P, Rotheneder H. EAPP: gatekeeper at the crossroad of apoptosis and p21-mediated cell-cycle arrest. Oncogene. 2011;30:2679-90 pubmed publisher
	Nagy Z, Riss A, Fujiyama S, Krebs A, Orpinell M, Jansen P, et al. The metazoan ATAC and SAGA coactivator HAT complexes regulate different sets of inducible target genes. Cell Mol Life Sci. 2010;67:611-28 pubmed publisher
	Ferreira R, Eberharter A, Bonaldi T, Chioda M, Imhof A, Becker P. Site-specific acetylation of ISWI by GCN5. BMC Mol Biol. 2007;8:73 pubmed
	Guenatri M, Bailly D, Maison C, Almouzni G. Mouse centric and pericentric satellite repeats form distinct functional heterochromatin. J Cell Biol. 2004;166:493-505 pubmed

product information

Catalog Number :

05-598

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-phospho-Histone H3 (Ser10) Antibody, clone RR002

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q16695

Host Name :

Mouse

Antigen :

phospho-Histone H3 (Ser10)

Clone :

RR002

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-phospho-Histone H3 (Ser10) Antibody, clone RR002

Cross Reactivity :

Human;Vertebrates;Nematode

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

ALT Names :

H3 histone, family 3A

Immunogen :

Peptide (ARK[pS]TGGKAPRKQL-C) corresponding to amino acids 7-20 of human histone H3 with a c-terminal cyteine added for conjugation purposes.

Specificity :

This antibody recognizes Histone H3 phosphorylated at Serine 10.

Package Size :

200 µg

Uses :

Immunocytochemistry;Immunohistochemistry;Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt