Nucleolin Antibody, clone 3G4B2 | EMD Millipore 05-565 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Nucleolin Antibody, clone 3G4B2

catalog :

05-565

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3G4B2

reactivity :

human, dogs

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 2

Reference
Hirata A, Nishiyama S, Tamura T, Yamauchi A, Hori H. Structural and functional analyses of the archaeal tRNA m2G/m22G10 methyltransferase aTrm11 provide mechanistic insights into site specificity of a tRNA methyltransferase that contains common RNA-binding modules. Nucleic Acids Res. 2016;44:6377-90 pubmed publisher
Luna L, Rolseth V, Hildrestrand G, Otterlei M, Dantzer F, Bjørås M, et al. Dynamic relocalization of hOGG1 during the cell cycle is disrupted in cells harbouring the hOGG1-Cys326 polymorphic variant. Nucleic Acids Res. 2005;33:1813-24 pubmed

product information

Catalog Number :

05-565

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Nucleolin Antibody, clone 3G4B2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P19338

Host Name :

Mouse

Antigen :

Nucleolin

Conjugate :

Culture Supernatant

Isotype :

IgG

Product Description :

Anti-Nucleolin Antibody, clone 3G4B2

Cross Reactivity :

Canine;Human;Monkey

Background :

Nucleolin, also known as C23, is the major nucleolar protein of exponentially growing eukaryotic cells. It is a ubiquitous conserved multi-domain phosphoprotein found in all vertebrate species. Nucleolin contains a specific bipartite nuclear localization signal sequence and three different structural domains. Nucleolin is a multifunctional protein involved in most steps of ribosome biogenesis. Nucleolin has been implicated in chromatin structure, rDNA transcription, rRNA maturation, ribosome assembly, cytokinesis, nucleogenesis, cell proliferation and growth, and nucleo-cytoplasmic transport. Nucleolin also exhibits autodegradation, DNA and RNA helicase activities, and DNA-dependent ATPase activity. Nucleolin activities may be regulated by proteolysis, methylation, ADPribosylation, and phosphorylation by several kinases, including casein kinase II (CK2), p34cdc2, and protein kinase C-ζ.

Immunogen :

Nuclear matrix extract from MDCK cells

Specificity :

nucleolin

Package Size :

100 µL

Uses :

Immunoprecipitation;Western Blotting;Immunocytochemistry

Storage :

2 years at -20°C