This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
TCF-4 Antibody, clone 6H5-3
catalog :
05-511
quantity :
200 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, EMSA, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - free floating section
citations: 30
Published Application/Species/Sample/Dilution | Reference |
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| Kim H, Kim J, Nam K, Kim W. Clinical significance of midkine expression in sporadic desmoid tumors. Oncol Lett. 2016;11:1677-1684 pubmed
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Yamada M, Ohnishi J, Ohkawara B, Iemura S, Satoh K, Hyodo Miura J, et al. NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF). J Biol Chem. 2006;281:20749-60 pubmed
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Sato S, Idogawa M, Honda K, Fujii G, Kawashima H, Takekuma K, et al. Beta-catenin interacts with the FUS proto-oncogene product and regulates pre-mRNA splicing. Gastroenterology. 2005;129:1225-36 pubmed
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Gottardi C, Gumbiner B. Distinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes. J Cell Biol. 2004;167:339-49 pubmed
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product information
Catalog Number :
05-511
Subcategory :
Epigenetics & Nuclear Function
Product Name :
Anti-TCF-4 Antibody, clone 6H5-3
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
Q9NQB0
Host Name :
Mouse
Antigen :
TCF-4
Clone :
6H5-3
Conjugate :
Purified
Isotype :
IgG2a
Product Description :
Anti-TCF-4 Antibody, clone 6H5-3
Cross Reactivity :
Human;Mouse
Background :
TCF4, also known as TCF7L2, is expressed widely during development. Gene targeting study indicates that it is required to maintain the crypt stem cells of the small intestine. TCF4 has many different splicing isoforms and they are expressed differentially in tissues and in cancers of different stages. Studies also indicate that variant of the TCF4 gene confers an increased risk of type 2 diabetes.
ALT Names :
HMG box transcription factor 4;Transcription factor 7-like 2;T-Cell factor 4;T-cell-specific, HMG box;T-Cell-specific transcription factor 4;Transcription factor 7-like 2
Immunogen :
Amino acids 31-331 of human TCF-4.
Specificity :
This antibody recognizes TCF-4
Package Size :
200 µg
Uses :
Electrophoretic Mobility Shift Assay;Immunocytochemistry;Immunohistochemistry;Immunoprecipitation;Western Blotting
Storage :
Stable for 1 year at -20ºC from date of receipt.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany
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