This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Bin1 Antibody, clone 99D
catalog :
05-449
quantity :
200 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
99D

The same clone is also sold as:
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; loading ...; fig 3j
  • western blot; mouse; loading ...; tbl 1
Cao M, Wu Y, Ashrafi G, McCartney A, Wheeler H, Bushong E, et al. Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons. Neuron. 2017;93:882-896.e5 pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; fig 4e
Ubelmann F, Burrinha T, Salavessa L, Gomes R, Ferreira C, Moreno N, et al. Bin1 and CD2AP polarise the endocytic generation of beta-amyloid. EMBO Rep. 2017;18:102-122 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:3200; fig 3
Adams S, Tilton K, Kozubek J, Seshadri S, Delalle I. Subcellular Changes in Bridging Integrator 1 Protein Expression in the Cerebral Cortex During the Progression of Alzheimer Disease Pathology. J Neuropathol Exp Neurol. 2016;75:779-790 pubmed
  • immunohistochemistry; mouse; loading ...; fig 4a
Lo H, Nixon S, Hall T, Cowling B, Ferguson C, Morgan G, et al. The caveolin-cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle. J Cell Biol. 2015;210:833-49 pubmed publisher
  • western blot; human
Zhou Y, Hayashi I, Wong J, Tugusheva K, Renger J, Zerbinatti C. Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein Tau in Alzheimer's disease. PLoS ONE. 2014;9:e103187 pubmed publisher
Chapuis J, Hansmannel F, Gistelinck M, Mounier A, Van Cauwenberghe C, Kolen K, et al. Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology. Mol Psychiatry. 2013;18:1225-34 pubmed publisher
product information
Catalog Number :
05-449
Subcategory :
Apoptosis & Cancer
Product Name :
Anti-Bin1 Antibody, clone 99D
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
O00499
Host Name :
Mouse
Antigen :
Bin1
Conjugate :
Purified
Isotype :
IgG1κ
Product Description :
Anti-Bin1 Antibody, clone 99D
Cross Reactivity :
Human;Mouse;Rat
Immunogen :
Partial fusion protein corresponding to amino acids 189-398 of human Bin1. Clone 99D
Specificity :
Bin1
Package Size :
200 µg
Uses :
Immunoprecipitation;Western Blotting;Immunohistochemistry
Storage :
1 year at -20°C
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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