Bin1, clone 99D (Ascites Free) | EMD Millipore 05-449-C product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Bin1, clone 99D (Ascites Free)

catalog :

05-449-C

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

99D

The same clone is also sold as:

BioLegend: 655602
MilliporeSigma: B9428
Boster: MA1005
Invitrogen: MA5-32996
OriGene: TA319582
Rockland Immunochemicals: 200-301-E60
Abnova: MAB1429
Santa Cruz Biotechnology: sc-13575

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; loading ...; fig 4a	Lo H, Nixon S, Hall T, Cowling B, Ferguson C, Morgan G, et al. The caveolin-cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle. J Cell Biol. 2015;210:833-49 pubmed publisher
	Chapuis J, Hansmannel F, Gistelinck M, Mounier A, Van Cauwenberghe C, Kolen K, et al. Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology. Mol Psychiatry. 2013;18:1225-34 pubmed publisher

product information

Catalog Number :

05-449-C

Subcategory :

Protein Trafficking

Product Name :

Anti-Bin1, clone 99D (Ascites Free)

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O00499

Host Name :

Mouse

Antigen :

BIN1

Clone :

99D

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG2bκ

Product Description :

Anti-Bin1, clone 99D (Ascites Free)

Cross Reactivity :

Human, Chicken, Mouse

Background :

Bin1, also known as Myc box-dependent-interacting protein 1, Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1, and encoded by the gene BIN1/AMPHL, is another protein involved in the regulation of synaptic vesicle endocytosis and interestingly also acts as tumor suppressor and inhibits malignant cell transformation. BIN1 is expressed in many tissues but has the highest expression in brain and muscle. BIN1 has isoforms and particular isoforms are expressed in particular tissues. For instance BIN1 isoform 11A is only expressed in the brain and found in axon initial segments and nodes of Ranvier. Mutations in BIN1 are associated with a disordered called centronuclear 2 myopathy. BIN1 is localized to nucleus but some isoforms are associated with cytoplasm.

ALT Names :

Myc box-dependent-interacting protein 1, Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1, Bin1

Immunogen :

Linear peptide corresponding to human Bin1.

Package Size :

100 μg

Uses :

Western Blotting, Immunohistochemistry, Immunoprecipitation, Flow Cytometry, Immunofluorescence

Storage :

Stable for 1 year at 2-8°C from date of receipt