VEGF Antibody, clone JH | EMD Millipore 05-443 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

VEGF Antibody, clone JH

catalog :

05-443

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

reactivity :

human, mouse

application :

immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; fig 3	Shukla P, Chaudhry K, Mir H, Gangwar R, Yadav N, Manda B, et al. Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation. BMC Cancer. 2016;16:189 pubmed publisher
immunohistochemistry - paraffin section; human; 1:500	Matsui T, Shigeta T, Umeda M, Komori T. Vascular endothelial growth factor C (VEGF-C) expression predicts metastasis in tongue cancer. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015;120:436-42 pubmed publisher
	Choi S, Kim M, Jeon J, Kim O, Choi Y, Seo J, et al. Active Immunization with Extracellular Vesicles Derived from Staphylococcus aureus Effectively Protects against Staphylococcal Lung Infections, Mainly via Th1 Cell-Mediated Immunity. PLoS ONE. 2015;10:e0136021 pubmed publisher
	Brodkorb F, Fischer B, Kalbfleisch K, Robers O, Braun C, Dohlen S, et al. Development of a New Monomer for the Synthesis of Intrinsic Antimicrobial Polymers with Enhanced Material Properties. Int J Mol Sci. 2015;16:20050-66 pubmed publisher
	Chau M, Deveau T, Song M, Gu X, Chen D, Wei L. iPSC Transplantation increases regeneration and functional recovery after ischemic stroke in neonatal rats. Stem Cells. 2014;32:3075-87 pubmed publisher
	Mosher K, Andres R, Fukuhara T, Bieri G, Hasegawa Moriyama M, He Y, et al. Neural progenitor cells regulate microglia functions and activity. Nat Neurosci. 2012;15:1485-7 pubmed publisher
	Ulici V, Hoenselaar K, Agoston H, McErlain D, Umoh J, Chakrabarti S, et al. The role of Akt1 in terminal stages of endochondral bone formation: angiogenesis and ossification. Bone. 2009;45:1133-45 pubmed publisher
	Long J, Jay S, Segal S, Madri J. VEGF-A and Semaphorin3A: modulators of vascular sympathetic innervation. Dev Biol. 2009;334:119-32 pubmed publisher

product information

Catalog Number :

05-443

Subcategory :

Cell Signaling

Product Name :

Anti-VEGF Antibody, clone JH

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P15692

Host Name :

Mouse

Antigen :

VEGF

Clone :

clone JH

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-VEGF Antibody, clone JH

Cross Reactivity :

Human;Mouse;Rat;Rabbit

Background :

The Flt gene family of receptor tyrosine kinases includes Flt-1, KDR/Flk-1, Flt-3, and Flt-4. They encode receptors for VEGF, characterized by seven Ig-loops within their extracellular domain and a split kinase domain within the cytoplasmic domain. VEGF is an important angiogenic factor of many solid tumors and is also involved in the differentiation of endothelial cells. Flt-1 (Fms-like tyrosine kinase, VEGF-R1) is expressed on endothelial cells and on the common precursors of endothelial and hematopoietic stem cells. KDR (Flk-1, VEGF-R2) is the principal receptor involved in VEGF signaling. KDR is expressed on endothelial cells and stimulates angiogenesis, but is also expressed on bone marrow cells, and is thought to play a role in driving the proliferation of most or all leukemic cells. Flt3 is a class III receptor tyrosine kinase that is closely related to c-Kit and c-Fms. It is expressed in primitive hematopoietic cells and its ligand exerts proliferative effects on these cells in co-operation with other cytokines. Flt3 is also expressed the placenta, testis, spleen, thymus, bone marrow, brain and in cerebellar Purkinje cells. The VEGF receptors stimulate the Ras-MAP kinase pathway, suggesting that it signals as a conventional receptor tyrosine kinase.

ALT Names :

Vascular permeability factor;vascular endothelial growth factor;vascular endothelial growth factor A;vascular endothelial growth factor isoform VEGF165

Immunogen :

Recombinant human VEGF121. Clone JH121

Specificity :

Recognizes 34-54 kDa isoforms of Vascular Endothelial Growth Factor/Vascular Permeability Factor (VEGF/VPF).

Package Size :

100 μg

Uses :

Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at from date of receipt.