NR1 Antibody, C Terminus, Alexa Fluor®488 Conjugate | EMD Millipore 05-432A4 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

NR1 Antibody, C Terminus, Alexa Fluor®488 Conjugate

catalog :

05-432A4

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

AF488

reactivity :

mouse, rat

application :

immunohistochemistry, immunocytochemistry

product information

Catalog Number :

05-432A4

Subcategory :

Neuroscience

Product Name :

Anti-NR1 Antibody, C Terminus, Alexa Fluor®488 Conjugate

Product Type :

Antibodies

Gene ID :

P35439

Host Name :

Mouse

Antigen :

NR1

Conjugate :

AlexaFluor®488

Isotype :

IgG

Product Description :

Anti-NR1 Antibody, C Terminus, Alexa Fluor®488 Conjugate

Cross Reactivity :

Mouse;Rat

Background :

NR1 (NMDA1or NMDAR1, also known as GRIN1) along with the NR2 subunit forms a heterodimer that make up the NMDA receptor. The NMDA receptor (NMDAR) is characterized as a ionotropic receptor for glutamate. As the name suggests, NMDA (N-methyl D-aspartate) is an agonist for the receptor. A distinct characteriztic of the NMDA receptor is that it is both ligand-gated and voltage-dependent based on its sensitivity to magnesium. Activated NMDA receptors result in the opening of an ion channel that is nonselective to cations. The result is the flow of Na+ and small amounts of Ca2+ ions into the cell and K+ out of the cell. Calcium flux by the NMDARs has been implicated in synaptic plasticity, a mechanism in the cell for learning and memory.

ALT Names :

Glutamate [NMDA] receptor subunit zeta-1;N-methyl-D-aspartate receptor subunit NR1;NMD-R1

Immunogen :

Recombinant protein corresponding to rat NR1.

Specificity :

This antibody maps to a region (834-864) common to all NR1 isoforms and so should cross react with all NR1 isoforms.

Package Size :

100 µL

Uses :

Immunocytochemistry;Immunohistochemistry

Storage :

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.