CrkL Antibody, clone 5-6 | EMD Millipore 05-414 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CrkL Antibody, clone 5-6

catalog :

05-414

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5-6

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunoprecipitation, other

citations: 2

Published Application/Species/Sample/Dilution	Reference
other; human; loading ...; fig st1	Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
western blot; human; tbl s3	Cheng H, Liang Y, Kuo Y, Chuu C, Lin C, Lee M, et al. Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data. Cell Death Dis. 2015;6:e1753 pubmed publisher

product information

Catalog Number :

05-414

Subcategory :

Cell Signaling

Product Name :

Anti-CrkL Antibody, clone 5-6

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P46109

Host Name :

Mouse

Antigen :

CrkL

Clone :

5-6

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-CrkL Antibody, clone 5-6

Cross Reactivity :

Human;Mouse;Rat

Background :

CRKL is a 39kDa adaptor protein with one SH2 and two SH3 binding domains. CRKL is the major protein which is tyrosine phosphorylated in response to BCR/ABL (chronic myelogenous leukemia) and growth factor activation. In myeloid cells, it binds to proteins such as paxillin, p130cas and p120 cbl. CRKL aslo appears to bind ABL and SOS. The antibody does not cross-react with CRKI or CRKII.

Immunogen :

Full length GST fusion protein corresponding to Human CRKL

Specificity :

the C-terminal SH3 of Human CRKL

Package Size :

100 µg

Uses :

Immunoprecipitation;Western Blotting;Immunohistochemistry

Storage :

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.