This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Na+/K+ ATPase α-1 Antibody, clone C464.6, Alexa Fluor® 555
catalog :
05-369X-555
quantity :
25 µg
clonality :
monoclonal
host :
mouse
conjugate :
Alexa Fluor 555
clone name :
C464.6
reactivity :
human, mouse, dogs
application :
western blot, immunocytochemistry, flow cytometry
citations: 45
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 6
Barceló C, Paco N, Beckett A, Alvarez Moya B, Garrido E, Gelabert M, et al. Oncogenic K-ras segregates at spatially distinct plasma membrane signaling platforms according to its phosphorylation status. J Cell Sci. 2013;126:4553-9 pubmed publisher
Kawano H, Sakamoto T, Ito T, Miyata K, Hashiguchi T, Maruyama I. Hyaluronan protection of corneal endothelial cells against extracellular histones after phacoemulsification. J Cataract Refract Surg. 2014;40:1885-93 pubmed publisher
Sun J, Hu F, Chen Y, Chu H, Chen W. Change of recipient corneal endothelial cells after non-descemet's stripping automated endothelial keratoplasty in a rabbit model. Invest Ophthalmol Vis Sci. 2014;55:8467-74 pubmed publisher
Lauf P, Alqahtani T, Flues K, Meller J, Adragna N. Interaction between Na-K-ATPase and Bcl-2 proteins BclXL and Bak. Am J Physiol Cell Physiol. 2015;308:C51-60 pubmed publisher
Resnier P, LeQuinio P, Lautram N, André E, Gaillard C, Bastiat G, et al. Efficient in vitro gene therapy with PEG siRNA lipid nanocapsules for passive targeting strategy in melanoma. Biotechnol J. 2014;9:1389-401 pubmed publisher
Skovgaard C, Christensen P, Larsen S, Andersen T, Thomassen M, Bangsbo J. Concurrent speed endurance and resistance training improves performance, running economy, and muscle NHE1 in moderately trained runners. J Appl Physiol (1985). 2014;117:1097-109 pubmed publisher
Schneppenheim J, Hüttl S, Kruchen A, Fluhrer R, Müller I, Saftig P, et al. Signal-peptide-peptidase-like 2a is required for CD74 intramembrane proteolysis in human B cells. Biochem Biophys Res Commun. 2014;451:48-53 pubmed publisher
Yan Y, Shapiro A, Haller S, Katragadda V, Liu L, Tian J, et al. Involvement of reactive oxygen species in a feed-forward mechanism of Na/K-ATPase-mediated signaling transduction. J Biol Chem. 2013;288:34249-58 pubmed publisher
de Juan Sanz J, Núñez E, Villarejo López L, Pérez Hernández D, Rodriguez Fraticelli A, López Corcuera B, et al. Na+/K+-ATPase is a new interacting partner for the neuronal glycine transporter GlyT2 that downregulates its expression in vitro and in vivo. J Neurosci. 2013;33:14269-81 pubmed publisher
Kaphzan H, Buffington S, Ramaraj A, Lingrel J, Rasband M, Santini E, et al. Genetic reduction of the ?1 subunit of Na/K-ATPase corrects multiple hippocampal phenotypes in Angelman syndrome. Cell Rep. 2013;4:405-12 pubmed publisher
Morita S, Tsuda T, Horikami M, Teraoka R, Kitagawa S, Terada T. Bile salt-stimulated phospholipid efflux mediated by ABCB4 localized in nonraft membranes. J Lipid Res. 2013;54:1221-30 pubmed publisher
Sumagin R, Robin A, Nusrat A, Parkos C. Activation of PKC?II by PMA facilitates enhanced epithelial wound repair through increased cell spreading and migration. PLoS ONE. 2013;8:e55775 pubmed publisher
Berret E, Nehme B, Henry M, Toth K, Drolet G, Mouginot D. Regulation of central Na+ detection requires the cooperative action of the NaX channel and ?1 Isoform of Na+/K+-ATPase in the Na+-sensor neuronal population. J Neurosci. 2013;33:3067-78 pubmed publisher
Evans J, Rodriguez S, Ragolia L. ACTH promotes chondrogenic nodule formation and induces transient elevations in intracellular calcium in rat bone marrow cell cultures via MC2-R signaling. Cell Tissue Res. 2013;352:413-25 pubmed publisher
Costa T, Amer A, Farag S, Wolf Watz H, Fallman M, Fahlgren A, et al. Type III secretion translocon assemblies that attenuate Yersinia virulence. Cell Microbiol. 2013;15:1088-110 pubmed publisher
Hatanaka H, Koizumi N, Okumura N, Takahashi H, Tanioka H, Young R, et al. A study of host corneal endothelial cells after non-Descemet stripping automated endothelial keratoplasty. Cornea. 2013;32:76-80 pubmed publisher
Mühlfeld S, Domanova O, Berlage T, Stross C, Helmer A, Keitel V, et al. Short-term feedback regulation of bile salt uptake by bile salts in rodent liver. Hepatology. 2012;56:2387-97 pubmed publisher
Petrushanko I, Yakushev S, Mitkevich V, Kamanina Y, Ziganshin R, Meng X, et al. S-glutathionylation of the Na,K-ATPase catalytic ? subunit is a determinant of the enzyme redox sensitivity. J Biol Chem. 2012;287:32195-205 pubmed publisher
Despa S, Lingrel J, Bers D. Na(+)/K)+)-ATPase α2-isoform preferentially modulates Ca2(+) transients and sarcoplasmic reticulum Ca2(+) release in cardiac myocytes. Cardiovasc Res. 2012;95:480-6 pubmed publisher
Tokhtaeva E, Clifford R, Kaplan J, Sachs G, Vagin O. Subunit isoform selectivity in assembly of Na,K-ATPase ?-? heterodimers. J Biol Chem. 2012;287:26115-25 pubmed publisher
Gunnarsson T, Bangsbo J. The 10-20-30 training concept improves performance and health profile in moderately trained runners. J Appl Physiol (1985). 2012;113:16-24 pubmed publisher
Evans J, Fernando A, Ragolia L. Functional melanocortin-2 receptors are expressed by mouse aorta-derived mesenchymal progenitor cells. Mol Cell Endocrinol. 2012;355:60-70 pubmed publisher
Kaphzan H, Buffington S, Jung J, Rasband M, Klann E. Alterations in intrinsic membrane properties and the axon initial segment in a mouse model of Angelman syndrome. J Neurosci. 2011;31:17637-48 pubmed publisher
Peruchetti D, Pinheiro A, Landgraf S, Wengert M, Takiya C, Guggino W, et al. (Na+ + K+)-ATPase is a target for phosphoinositide 3-kinase/protein kinase B and protein kinase C pathways triggered by albumin. J Biol Chem. 2011;286:45041-7 pubmed publisher
Makihira S, Nikawa H, Kajiya M, Kawai T, Mine Y, Kosaka E, et al. Blocking of sodium and potassium ion-dependent adenosine triphosphatase-?1 with ouabain and vanadate suppresses cell-cell fusion during RANKL-mediated osteoclastogenesis. Eur J Pharmacol. 2011;670:409-18 pubmed publisher
Groen A, Romero M, Kunne C, Hoosdally S, Dixon P, Wooding C, et al. Complementary functions of the flippase ATP8B1 and the floppase ABCB4 in maintaining canalicular membrane integrity. Gastroenterology. 2011;141:1927-37.e1-4 pubmed publisher
Watanabe R, Hayashi R, Kimura Y, Tanaka Y, Kageyama T, Hara S, et al. A novel gelatin hydrogel carrier sheet for corneal endothelial transplantation. Tissue Eng Part A. 2011;17:2213-9 pubmed publisher
Basevich E, Lopina O, Rubtsov A. Seasonal changes in microsomal fraction enriched with Na,K-ATPase from kidneys of the ground squirrel Spermophilus undulatus. Biochemistry (Mosc). 2010;75:1408-16 pubmed
Gildea J, Kemp B, Howell N, Van Sciver R, Carey R, Felder R. Inhibition of renal caveolin-1 reduces natriuresis and produces hypertension in sodium-loaded rats. Am J Physiol Renal Physiol. 2011;300:F914-20 pubmed publisher
Proulx S, d Arc Uwamaliya J, Carrier P, Deschambeault A, Audet C, Giasson C, et al. Reconstruction of a human cornea by the self-assembly approach of tissue engineering using the three native cell types. Mol Vis. 2010;16:2192-201 pubmed
Hisano Y, Kobayashi N, Kawahara A, Yamaguchi A, Nishi T. The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720. J Biol Chem. 2011;286:1758-66 pubmed publisher
Tokhtaeva E, Sachs G, Vagin O. Diverse pathways for maturation of the Na,K-ATPase ?1 and ?2 subunits in the endoplasmic reticulum of Madin-Darby canine kidney cells. J Biol Chem. 2010;285:39289-302 pubmed publisher
Chen X, Fahy A, Green A, Anderson M, Rhoads R, Limesand S. ?2-Adrenergic receptor desensitization in perirenal adipose tissue in fetuses and lambs with placental insufficiency-induced intrauterine growth restriction. J Physiol. 2010;588:3539-49 pubmed publisher
Törmäkangas L, Markkula E, Lounatmaa K, Puolakkainen M. Chlamydia pneumoniae infection in polarized epithelial cell lines. Infect Immun. 2010;78:2714-22 pubmed publisher
Thomassen M, Christensen P, Gunnarsson T, Nybo L, Bangsbo J. Effect of 2-wk intensified training and inactivity on muscle Na+-K+ pump expression, phospholemman (FXYD1) phosphorylation, and performance in soccer players. J Appl Physiol (1985). 2010;108:898-905 pubmed publisher
Egaña L, Cuevas R, Baust T, Parra L, Leak R, Hochendoner S, et al. Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3. J Neurosci. 2009;29:4592-604 pubmed publisher
Proulx S, Bensaoula T, Nada O, Audet C, d Arc Uwamaliya J, Devaux A, et al. Transplantation of a tissue-engineered corneal endothelium reconstructed on a devitalized carrier in the feline model. Invest Ophthalmol Vis Sci. 2009;50:2686-94 pubmed publisher
Proulx S, Audet C, Uwamaliya J, Deschambeault A, Carrier P, Giasson C, et al. Tissue engineering of feline corneal endothelium using a devitalized human cornea as carrier. Tissue Eng Part A. 2009;15:1709-18 pubmed publisher
Hazelwood L, Free R, Cabrera D, Skinbjerg M, Sibley D. Reciprocal modulation of function between the D1 and D2 dopamine receptors and the Na+,K+-ATPase. J Biol Chem. 2008;283:36441-53 pubmed publisher
Ito D, Fujisawa T, Iida H, Suzuki N. Characterization of seipin/BSCL2, a protein associated with spastic paraplegia 17. Neurobiol Dis. 2008;31:266-77 pubmed publisher
Pastrana D, Yun C, McKee M, FitzGerald D. Mammalian cell expression of an active site mutant of Pseudomonas exotoxin disrupts LRP1 maturation. J Biomed Sci. 2008;15:427-39 pubmed publisher
Okkenhaug H, Weylandt K, Carmena D, Wells D, Higgins C, Sardini A. The human ClC-4 protein, a member of the CLC chloride channel/transporter family, is localized to the endoplasmic reticulum by its N-terminus. FASEB J. 2006;20:2390-2 pubmed
Ohashi S, Mori A, Kurihara N, Mitsumoto Y, Nakai M. Age-related severity of dopaminergic neurodegeneration to MPTP neurotoxicity causes motor dysfunction in C57BL/6 mice. Neurosci Lett. 2006;401:183-7 pubmed
Doran P, Dowling P, Donoghue P, Buffini M, Ohlendieck K. Reduced expression of regucalcin in young and aged mdx diaphragm indicates abnormal cytosolic calcium handling in dystrophin-deficient muscle. Biochim Biophys Acta. 2006;1764:773-85 pubmed
Mori A, Ohashi S, Nakai M, Moriizumi T, Mitsumoto Y. Neural mechanisms underlying motor dysfunction as detected by the tail suspension test in MPTP-treated C57BL/6 mice. Neurosci Res. 2005;51:265-74 pubmed
product information
Catalog Number :
05-369X-555
Subcategory :
Neuroscience
Product Name :
Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6, Alexa Fluor® 555
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P13637
Host Name :
Mouse
Antigen :
Na+/K+ ATPase α-1
Clone :
C464.6
Conjugate :
Purified
Isotype :
IgG1
Product Description :
Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6, Alexa Fluor® 555
Cross Reactivity :
Canine;Human;Mouse;Monkey;Pig;Rat;Rabbit;Sheep;Xenopus
Immunogen :
Purified Na+/K+ ATPase isolated from membrane fractions of rabbit kidney outer medulla.
Specificity :
Specific for the α-1 subunit isoform.
Package Size :
25 µg
Uses :
Flow Cytometry;Immunofluorescence;Western Blotting
Storage :
Do Not Freeze. Do not store the material diluted. Stable for 1 year at 4°C from date of shipment. For maximum recovery of product, centrifuge original vial prior to removing cap.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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