Cyclin E Antibody, clone HE12 | EMD Millipore 05-363 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Cyclin E Antibody, clone HE12

catalog :

05-363

quantity :

200 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HE12

The same clone is also sold as:

LifeSpan Biosciences: LS-C22558, LS-C88539, LS-C88540, LS-C179701
Santa Cruz Biotechnology: sc-247
Abcam: ab3927
BD Biosciences: 551159, 551160
Invitrogen: 50-9714-80, 32-1600, MA5-14336, 13-9714-82
OriGene: DM266, DM266-05
Cell Signaling Technology: 4129

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig s4b	He P, Yang J, Yang V, Bialkowska A. Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice. Gastroenterology. 2018;154:1494-1508.e13 pubmed publisher
western blot; rat; 1:1000	Tang N, Lyu D, Liu T, Chen F, Jing S, Hao T, et al. Different Effects of p52SHC1 and p52SHC3 on the Cell Cycle of Neurons and Neural Stem Cells. J Cell Physiol. 2016;231:172-80 pubmed publisher

product information

Catalog Number :

05-363

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Cyclin E Antibody, clone HE12

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P24864

Host Name :

Mouse

Antigen :

Cyclin E

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-Cyclin E Antibody, clone HE12

Cross Reactivity :

Human

Background :

Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

Immunogen :

Recombinant human cyclin E

Specificity :

human p52cyclin E

Package Size :

200 µg

Uses :

Immunoprecipitation;Western Blotting;Immunocytochemistry

Storage :

2 years at -20°C or 6 months at 4°C