PCNA Antibody, clone PC10 | EMD Millipore 05-347 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PCNA Antibody, clone PC10

catalog :

05-347

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PC10

The same clone is also sold as:

OriGene: AM10035PU-N, AM10035PU-S, TA309795
BioLegend: 307912, 307914, 307908, 307904, 307902, 307909, 307901
GeneTex: GTX20029
Santa Cruz Biotechnology: sc-56 HRP, sc-56 AC, sc-56
LifeSpan Biosciences: LS-C87503, LS-C87459, LS-C358014, LS-C9535, LS-C43736, LS-C87502, LS-C170844, LS-B9987, LS-C86889, LS-B3434
Enzo Life Sciences: ALX-801-091-L001
Bio-Rad: MCA1558P, MCA1558F, MCA1558
Invitrogen: MA5-11358, 13-3900, 13-3940
Novus Biologicals: NBP2-80905, NB500-106
Exbio: 1P-182-T025, 11-182-C100, 1P-182-T100
Cell Signaling Technology: 2586, 8580
Abcam: ab29

reactivity :

human, rat, zebrafish

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 6a	Wilson R, Biasutto A, Wang L, Fischer R, Baple E, Crosby A, et al. PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions. DNA Repair (Amst). 2017;50:22-35 pubmed publisher
immunohistochemistry - paraffin section; zebrafish ; 1:100; fig 5	He S, Mansour M, Zimmerman M, Ki D, Layden H, Akahane K, et al. Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain. elife. 2016;5: pubmed publisher
	Feng M, Shu Y, Yang Y, Zheng X, Li R, Wang Y, et al. Ulinastatin attenuates experimental autoimmune encephalomyelitis by enhancing anti-inflammatory responses. Neurochem Int. 2014;64:64-72 pubmed publisher
	Kashiwagi K, Nimura K, Ura K, Kaneda Y. DNA methyltransferase 3b preferentially associates with condensed chromatin. Nucleic Acids Res. 2011;39:874-88 pubmed publisher
	Stevens H, Smith K, Maragnoli M, Fagel D, Borok E, Shanabrough M, et al. Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits. J Neurosci. 2010;30:5590-602 pubmed publisher

product information

Catalog Number :

05-347

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-PCNA Antibody, clone PC10

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P12004

Host Name :

Mouse

Antigen :

PCNA

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-PCNA Antibody, clone PC10

Cross Reactivity :

Vertebrates

Background :

Expression of proliferating cell nuclear antigen (PCNA), cyclin or polymerase delta auxiliary protein is elevated in the nucleus during late G1 phase immediately before the onset of DNA synthesis, becoming maximal during S-phase and declining during G2 and M phases. PCNA/cyclin may act as an auxiliary protein of DNA polymerase-delta to play a fundamental role in the initiation of cell proliferation. Anti-PCNA reacts with PCNA at the molecular weight of 36 kDa on western blot.

Immunogen :

Recombinant rat PCNA

Specificity :

PCNA

Package Size :

100 µg

Uses :

Western Blotting;Immunocytochemistry;Immunohistochemistry

Storage :

2 years at -20°C