Nitrotyrosine Antibody, clone 1A6 | EMD Millipore 05-233 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Nitrotyrosine Antibody, clone 1A6

catalog :

05-233

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1A6

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 22

Reference
Xue X, Bredell B, Anderson E, Martin A, Mays C, Nagao Kitamoto H, et al. Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer. Proc Natl Acad Sci U S A. 2017;114:E9608-E9617 pubmed publisher
Wang H, Tao L, Ambrosio A, Yan W, Summer R, Lau W, et al. T-cadherin deficiency increases vascular vulnerability in T2DM through impaired NO bioactivity. Cardiovasc Diabetol. 2017;16:12 pubmed publisher
Shosha E, Xu Z, Yokota H, Saul A, Rojas M, Caldwell R, et al. Arginase 2 promotes neurovascular degeneration during ischemia/reperfusion injury. Cell Death Dis. 2016;7:e2483 pubmed publisher
Nag T, Wadhwa S. Immunolocalisation pattern of complex I-V in ageing human retina: Correlation with mitochondrial ultrastructure. Mitochondrion. 2016;31:20-32 pubmed publisher
Kim S, Chung Y, Lee H, Chung S, Lee J, Sohn U, et al. Protective effects of phosphatidylcholine on oxaliplatin-induced neuropathy in rats. Life Sci. 2015;130:81-7 pubmed publisher
Yu Q, Liu B, Ruan D, Niu C, Shen J, Ni M, et al. A novel targeted proteomics method for identification and relative quantitation of difference in nitration degree of OGDH between healthy and diabetic mouse. Proteomics. 2014;14:2417-26 pubmed publisher
Herrera E, Macchiavello R, Montt C, Ebensperger G, Diaz M, Ramirez S, et al. Melatonin improves cerebrovascular function and decreases oxidative stress in chronically hypoxic lambs. J Pineal Res. 2014;57:33-42 pubmed publisher
Cong W, Zhao T, Zhu Z, Huang B, Ma W, Wang Y, et al. Metallothionein prevents cardiac pathological changes in diabetes by modulating nitration and inactivation of cardiac ATP synthase. J Nutr Biochem. 2014;25:463-74 pubmed publisher
Chen Y, Liu S, Hu D, Xing Y, Shen Y. N -methyl- N -nitrosourea-induced retinal degeneration in mice. Exp Eye Res. 2014;121:102-13 pubmed publisher
Ryan K, Liang L, Rivard C, Patel M. Temporal and spatial increase of reactive nitrogen species in the kainate model of temporal lobe epilepsy. Neurobiol Dis. 2014;64:8-15 pubmed publisher
Sen S, Kawahara B, Fry N, Farias Eisner R, Zhang D, Mascharak P, et al. A light-activated NO donor attenuates anchorage independent growth of cancer cells: Important role of a cross talk between NO and other reactive oxygen species. Arch Biochem Biophys. 2013;540:33-40 pubmed publisher
Bayliss C, Jacques A, Leung M, Ward D, Redwood C, Gallon C, et al. Myofibrillar Ca(2+) sensitivity is uncoupled from troponin I phosphorylation in hypertrophic obstructive cardiomyopathy due to abnormal troponin T. Cardiovasc Res. 2013;97:500-8 pubmed publisher
Feine I, Pinkas I, Salomon Y, Scherz A. Local oxidative stress expansion through endothelial cells--a key role for gap junction intercellular communication. PLoS ONE. 2012;7:e41633 pubmed publisher
Lopez Andres N, Tesse A, Regnault V, Louis H, Cattan V, Thornton S, et al. Increased microparticle production and impaired microvascular endothelial function in aldosterone-salt-treated rats: protective effects of polyphenols. PLoS ONE. 2012;7:e39235 pubmed publisher
Sasser J, Moningka N, Tsarova T, Baylis C. Nebivolol does not protect against 5/6 ablation/infarction induced chronic kidney disease in rats - comparison with angiotensin II receptor blockade. Life Sci. 2012;91:54-63 pubmed publisher
Furukawa Hibi Y, Alkam T, Nitta A, Matsuyama A, Mizoguchi H, Suzuki K, et al. Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-Î² peptide in mice. Behav Brain Res. 2011;225:222-9 pubmed publisher
Banday A, Lokhandwala M. Angiotensin II-mediated biphasic regulation of proximal tubular Na+/H+ exchanger 3 is impaired during oxidative stress. Am J Physiol Renal Physiol. 2011;301:F364-70 pubmed publisher
Broadwater L, Pandit A, Clements R, Azzam S, Vadnal J, Sulak M, et al. Analysis of the mitochondrial proteome in multiple sclerosis cortex. Biochim Biophys Acta. 2011;1812:630-41 pubmed publisher
Mastronardi M, Mostefai H, Soleti R, Agouni A, Martinez M, Andriantsitohaina R. Microparticles from apoptotic monocytes enhance nitrosative stress in human endothelial cells. Fundam Clin Pharmacol. 2011;25:653-60 pubmed publisher
Osoata G, Yamamura S, Ito M, Vuppusetty C, Adcock I, Barnes P, et al. Nitration of distinct tyrosine residues causes inactivation of histone deacetylase 2. Biochem Biophys Res Commun. 2009;384:366-71 pubmed publisher
Addabbo F, Ratliff B, Park H, Kuo M, Ungvari Z, Csiszar A, et al. The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. Am J Pathol. 2009;174:34-43 pubmed publisher
Martin L, Liu Z, Chen K, Price A, Pan Y, Swaby J, et al. Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death. J Comp Neurol. 2007;500:20-46 pubmed

product information

Catalog Number :

05-233

Subcategory :

Neuroscience

Product Name :

Anti-Nitrotyrosine Antibody, clone 1A6

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Mouse

Antigen :

Nitrotyrosine

Clone :

1A6

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-Nitrotyrosine Antibody, clone 1A6

Cross Reactivity :

Vertebrates

Background :

Nitrotyrosine has been identified as an indicator of cell damage and inflammation, as well as of the production of NO. It is believed that measuring the concentration of nitrotyrosine will serve as a marker for damage caused by NO in the cell. Previous studies have shown that nitrotyrosine has been found in inflammatory conditions such as atherosclerotic plaques and rheumatoid arthritis, among others

Immunogen :

Nitrated KLH

Specificity :

Recognizes nitrated protein.

Package Size :

100 μg

Uses :

Immunocytochemistry;Immunohistochemistry;Immunoprecipitation;Western Blotting

Storage :

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.