trimethyl Histone H3 (Lys27) Antibody, clone 18E9.1 | EMD Millipore 05-1951 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

trimethyl Histone H3 (Lys27) Antibody, clone 18E9.1

catalog :

05-1951

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

18E9.1

reactivity :

human, mouse

application :

western blot, immunocytochemistry, ChIP-Seq

citations: 2

Published Application/Species/Sample/Dilution	Reference
ChIP-Seq; mouse; loading ...; fig st2 western blot; mouse; loading ...; fig 3a western blot; human; loading ...; fig 3a	Zhong J, Li X, Cai W, Wang Y, Dong S, Yang J, et al. TET1 modulates H4K16 acetylation by controlling auto-acetylation of hMOF to affect gene regulation and DNA repair function. Nucleic Acids Res. 2017;45:672-684 pubmed publisher
western blot; human; 1:15,000; loading ...; fig 4a	Badal S, Her Y, Maher L. Nonantibiotic Effects of Fluoroquinolones in Mammalian Cells. J Biol Chem. 2015;290:22287-97 pubmed publisher

product information

Catalog Number :

05-1951

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-trimethyl Histone H3 (Lys27) Antibody, clone 18E9.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P84243

Host Name :

Mouse

Antigen :

trimethyl Histone H3 (Lys27)

Clone :

18E9.1

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-trimethyl Histone H3 (Lys27) Antibody, clone 18E9.1

Cross Reactivity :

Human;Mouse

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

ALT Names :

H3K27me3;Histone H3 (tri methyl K27);H3 histone family, member T;histone 3, H3;histone cluster 3, H3

Immunogen :

Linear peptide corresponding to human Histone H3 trimethylated at Lys27.

Specificity :

This antibody recognizes Histone H3 trimethylated at Lys27.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry;Dot Blot

Storage :

Stable for 1 year at 2-8°C from date of receipt