This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
PDK Antibody, clone 3H1.2
catalog :
05-1912
quantity :
100 μg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3H1.2
reactivity :
human
application :
western blot, immunocytochemistry
product information
Catalog Number :
05-1912
Subcategory :
Cell Signaling
Product Name :
Anti-PDK Antibody, clone 3H1.2
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
Q15118
Host Name :
Mouse
Antigen :
PDK
Clone :
3H1.2
Conjugate :
Purified
Isotype :
IgMκ
Product Description :
Anti-PDK Antibody, clone 3H1.2
Cross Reactivity :
Human;Rat
Background :
Pyruvate dehydrogenase kinase (PDK) is a mitochondrial enzyme important in metabolism that controls the pyruvate dehydrogenase complex and links glycolysis to the citric acid cycle. PDK is thought to regulate all aerobic oxidation of carbohydrates. Interestingly, inhibition of PDK disrupts glycolysis and increases mitochondrial respiration which causes a decrease in colorectal cancer cell proliferation, without effecting non-cancerous cells.
ALT Names :
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial;Pyruvate dehydrogenase kinase isoform 1
Immunogen :
KLH-conjugated linear peptide corresponding to human PDK.
Package Size :
100 μg
Uses :
Western Blotting;Immunocytochemistry
Storage :
Stable for 1 year at 2-8°C from date of receipt
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany
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