FAK Antibody, clone 2A7 | EMD Millipore 05-182 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

FAK Antibody, clone 2A7

catalog :

05-182

quantity :

200 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2A7

reactivity :

human, mouse, rat, Xenopus laevis

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; Xenopus laevis; 1:500	Bjerke M, Dzamba B, Wang C, DeSimone D. FAK is required for tension-dependent organization of collective cell movements in Xenopus mesendoderm. Dev Biol. 2014;394:340-56 pubmed publisher
immunohistochemistry; human; 1:200	Aust S, Auer K, Bachmayr Heyda A, Denkert C, Sehouli J, Braicu I, et al. Ambivalent role of pFAK-Y397 in serous ovarian cancer--a study of the OVCAD consortium. Mol Cancer. 2014;13:67 pubmed publisher
immunoprecipitation; rat immunocytochemistry; rat western blot; rat immunoprecipitation; mouse western blot; mouse	Wakatsuki S, Araki T, Sehara Fujisawa A. Neuregulin-1/glial growth factor stimulates Schwann cell migration by inducing ?5 ?1 integrin-ErbB2-focal adhesion kinase complex formation. Genes Cells. 2014;19:66-77 pubmed publisher
immunocytochemistry; mouse	Koch S, Scifo E, Rokka A, Trippner P, Lindfors M, Korhonen R, et al. Cathepsin D deficiency induces cytoskeletal changes and affects cell migration pathways in the brain. Neurobiol Dis. 2013;50:107-19 pubmed publisher
	Kamarajan P, Bunek J, Lin Y, Nunez G, Kapila Y. Receptor-interacting protein shuttles between cell death and survival signaling pathways. Mol Biol Cell. 2010;21:481-8 pubmed publisher
	Kamarajan P, Kapila Y. An altered fibronectin matrix induces anoikis of human squamous cell carcinoma cells by suppressing integrin alpha v levels and phosphorylation of FAK and ERK. Apoptosis. 2007;12:2221-31 pubmed
	Tsuji T, Ishizaki T, Okamoto M, Higashida C, Kimura K, Furuyashiki T, et al. ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts. J Cell Biol. 2002;157:819-30 pubmed
	Aplin A, Stewart S, Assoian R, Juliano R. Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1. J Cell Biol. 2001;153:273-82 pubmed
	Petit V, Boyer B, Lentz D, Turner C, Thiery J, Valles A. Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells. J Cell Biol. 2000;148:957-70 pubmed

product information

Catalog Number :

05-182

Subcategory :

Cell Signaling

Product Name :

Anti-FAK Antibody, clone 2A7

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q05397

Host Name :

Mouse

Antigen :

FAK

Clone :

2A7

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-FAK Antibody, clone 2A7

Cross Reactivity :

Avian;Human;Mouse;Rat

Immunogen :

Mixture of affinity-purified tyrosine phosphoproteins from chick embryo fibroblasts expressing p125FAK.

Specificity :

Recognizes FAK.

Package Size :

200 μg

Uses :

Immunocytochemistry;Immunoprecipitation

Storage :

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.