IGF-II Antibody, clone S1F2 | EMD Millipore 05-166 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

IGF-II Antibody, clone S1F2

catalog :

05-166

quantity :

500 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S1F2

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:500; loading ...; fig 8	Mellott T, Huleatt O, Shade B, Pender S, Liu Y, Slack B, et al. Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice. PLoS ONE. 2017;12:e0170450 pubmed publisher
immunohistochemistry - paraffin section; human; loading ...	Boo H, Min H, Jang H, Yun H, Smith J, Jin Q, et al. The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells. Nat Commun. 2016;7:12961 pubmed publisher
western blot; human	Ferraro Z, Qiu Q, Gruslin A, Adamo K. Excessive gestational weight gain and obesity contribute to altered expression of maternal insulin-like growth factor binding protein-3. Int J Womens Health. 2013;5:657-65 pubmed publisher
	Gao H, Sathishkumar K, Yallampalli U, Balakrishnan M, Li X, Wu G, et al. Maternal protein restriction regulates IGF2 system in placental labyrinth. Front Biosci (Elite Ed). 2012;4:1434-50 pubmed
	Jaafar R, Zeiller C, Pirola L, Di Grazia A, Naro F, Vidal H, et al. Phospholipase D regulates myogenic differentiation through the activation of both mTORC1 and mTORC2 complexes. J Biol Chem. 2011;286:22609-21 pubmed publisher

product information

Catalog Number :

05-166

Subcategory :

Cell Signaling

Product Name :

Anti-IGF-II Antibody, clone S1F2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P01344

Host Name :

Mouse

Antigen :

IGF-II

Clone :

S1F2

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-IGF-II Antibody, clone S1F2

Cross Reactivity :

Human;Rat

Background :

Human Insulin-like Growth Factor II (IGFII) contains 67 amino acids and shares similar structural features with IGFI, including a 62% sequence homology. In human plasma, IGFI and IGFII are associated with IGF-binding proteins that transport the polypeptides and partially regulate their actions in vivo. In addition to the insulin receptor, IGFII binds to two forms of IGF receptors, both of which are widely distributed in different tissues and cultured cells. IGFII is mitogenic for a variety of cultured cells, including mouse 3T3 cells,12 normal rat kidney cells, human or chicken fibroblasts and MCF-7 human breast carcinoma cells.

Immunogen :

Partially purified rat IGF-II. Clone S1F2

Specificity :

This antibody detects IGF-II.

Package Size :

500 µg

Uses :

ELISA;Immunoprecipitation;Immunocytochemistry;Neutralizing;Western Blotting

Storage :

Stable for 1 year at -20ºC from date of receipt.