PRL-2 Antibody, clone 42 | EMD Millipore 05-1583 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PRL-2 Antibody, clone 42

catalog :

05-1583

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

reactivity :

hamsters, human, mouse

application :

western blot, immunohistochemistry, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; hamsters; fig 5	Moerdyk Schauwecker M, Hwang S, Grdzelishvili V. Cellular proteins associated with the interior and exterior of vesicular stomatitis virus virions. PLoS ONE. 2014;9:e104688 pubmed publisher

product information

Catalog Number :

05-1583

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-PRL-2 Antibody, clone 42

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O70274

Host Name :

Mouse

Antigen :

PRL-2

Clone :

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-PRL-2 Antibody, clone 42

Cross Reactivity :

Human;Mouse

Background :

PRL-2 is one of three members (PRL-1, PRL-2, and PRL-3) that is part of a unique protein-tyrosine phosphatase ((PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP is known to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferres a transformed phenotype and can result in a tumor growth in nude mice, suggesting a role in tumorigenesis. Alternatively spliced transcript variants that encode two distinct isoforms have been described

ALT Names :

Protein-tyrosine phosphatase 4a2;Protein-tyrosine phosphatase of regenerating liver 2;phosphatase of regenerating liver 2;protein tyrosine phosphatase IVA;protein tyrosine phosphatase IVA2;protein tyrosine phosphatase type IVA, member 2

Immunogen :

GST-tagged recombinant protein corresponding to mouse PRL-2.

Specificity :

This antibody recognizes PRL-2.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry;Immunoprecipitation

Storage :

Stable for 1 year at 2-8°C from date of receipt