Axin-1 Antibody, clone A5 | EMD Millipore 05-1579 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Axin-1 Antibody, clone A5

catalog :

05-1579

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:100 western blot; human; 1:500	Fan C, Jiang G, Zhang X, Miao Y, Lin X, Luan L, et al. Zbed3 contributes to malignant phenotype of lung cancer via regulating Î²-catenin and P120-catenin 1. Mol Carcinog. 2015;54 Suppl 1:E138-47 pubmed publisher

product information

Catalog Number :

05-1579

Subcategory :

Cell Signaling

Product Name :

Anti-Axin-1 Antibody, clone A5

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O35625

Host Name :

Mouse

Antigen :

Axin-1

Clone :

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-Axin-1 Antibody, clone A5

Cross Reactivity :

Human;Mouse

Background :

Axin-1 is constitutively expressed and acts as a negative regulator of Wnt expression. It has been demonstrated that mouse Wnt, Wnt3a, is secreted by multiple cell lines and can act and as a growth factor for stem cells. Secreted Wnt3a is highly hydrophobic because it is palmitoylated on an essential cysteine C77; the palmitoylated state of Wnt3a is essential for stem cell signaling. Incubation of stem cells with Wnt3a in tissue culture medium resulted in the increased number of mouse hematopoietic stem cells expressing "primitive" phenotype.

ALT Names :

Axis inhibition protein 1;axin 1;axis inhibitor 1;fused, mouse, homolog of

Immunogen :

GST-tagged recombinant protein corresponding to the N-terminus of mouse Axin-1.

Specificity :

This antibody recognizes the N-terminus of Axin-1.

Package Size :

100 μg

Uses :

Western Blotting;Immunoprecipitation;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt