MAP Kinase 2/Erk2 Antibody, clone 1B3B9 | EMD Millipore 05-157 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MAP Kinase 2/Erk2 Antibody, clone 1B3B9

catalog :

05-157

quantity :

200 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1B3B9

The same clone is also sold as:

MilliporeSigma: M7431

reactivity :

human, mouse

application :

western blot, immunoprecipitation

citations: 12

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:2000; loading ...; fig e7j	Ramírez C, Hauser A, Vucic E, Bar Sagi D. Plasma membrane V-ATPase controls oncogenic RAS-induced macropinocytosis. Nature. 2019;576:477-481 pubmed publisher
western blot; human; loading ...; fig 5b,5c,6b,6c,6d	Pomares H, Palmeri C, Iglesias Serret D, Moncunill Massaguer C, Saura Esteller J, Núñez Vázquez S, et al. Targeting prohibitins induces apoptosis in acute myeloid leukemia cells. Oncotarget. 2016;7:64987-65000 pubmed publisher
western blot; human; 1:250; fig 2	Hattermann K, Gebhardt H, Krossa S, Ludwig A, Lucius R, Held Feindt J, et al. Transmembrane chemokines act as receptors in a novel mechanism termed inverse signaling. elife. 2016;5:e10820 pubmed publisher
western blot; human; loading ...; fig s4d	Moncunill Massaguer C, Saura Esteller J, PÃ©rez Perarnau A, Palmeri C, NÃºÃ±ez VÃ¡zquez S, Cosialls A, et al. A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation. Oncotarget. 2015;6:41750-65 pubmed publisher
western blot; mouse; fig 1	Alexandrova E, Yallowitz A, Li D, Xu S, Schulz R, Proia D, et al. Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment. Nature. 2015;523:352-6 pubmed publisher
	Ischenko I, Liu J, Petrenko O, Hayman M. Transforming growth factor-beta signaling network regulates plasticity and lineage commitment of lung cancer cells. Cell Death Differ. 2014;21:1218-28 pubmed publisher
	Yallowitz A, Alexandrova E, Talos F, Xu S, Marchenko N, Moll U. p63 is a prosurvival factor in the adult mammary gland during post-lactational involution, affecting PI-MECs and ErbB2 tumorigenesis. Cell Death Differ. 2014;21:645-54 pubmed publisher
	Alexandrova E, Petrenko O, Nemajerova A, Romano R, Sinha S, Moll U. ?Np63 regulates select routes of reprogramming via multiple mechanisms. Cell Death Differ. 2013;20:1698-708 pubmed publisher
	Bonito N, Drechsler J, Stoecker S, Carmo C, Seckl M, Hermanns H, et al. Control of gp130 expression by the mitogen-activated protein kinase ERK2. Oncogene. 2014;33:2255-63 pubmed publisher
	González Gironès D, Moncunill Massaguer C, Iglesias Serret D, Cosialls A, Pérez Perarnau A, Palmeri C, et al. AICAR induces Bax/Bak-dependent apoptosis through upregulation of the BH3-only proteins Bim and Noxa in mouse embryonic fibroblasts. Apoptosis. 2013;18:1008-16 pubmed publisher
	Upadhya D, Ogata M, Reneker L. MAPK1 is required for establishing the pattern of cell proliferation and for cell survival during lens development. Development. 2013;140:1573-82 pubmed publisher
	Haller F, Löbke C, Ruschhaupt M, Schulten H, Schwager S, Gunawan B, et al. Increased KIT signalling with up-regulation of cyclin D correlates to accelerated proliferation and shorter disease-free survival in gastrointestinal stromal tumours (GISTs) with KIT exon 11 deletions. J Pathol. 2008;216:225-35 pubmed publisher

product information

Catalog Number :

05-157

Subcategory :

Cell Signaling

Product Name :

Anti-MAP Kinase 2/Erk2 Antibody, clone 1B3B9

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P28482

Host Name :

Mouse

Antigen :

MAP Kinase 2/Erk2

Clone :

1B3B9

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-MAP Kinase 2/Erk2 Antibody, clone 1B3B9

Cross Reactivity :

Avian;Human;Mouse;Rat

Background :

ERK2 is activated by MEK2, which phosphorylates neighboring threonine 183 and tyrosine 185 residues. ERK2 is a serine/threonine kinase that phosphorylates MAP2 and myelin basic protein. This kinase is an important proximal component of the MAP kinase pathway involved in transeitting the signals from growth factors, neurotransmitters and hormones at the cell surface to the transcriptional events in the nucleus.

ALT Names :

Extracellular signal-regulated kinase 2;MAP kinase 2;MAPK 2;Mitogen-activated protein kinase 2;extracellular signal-regulated kinase-2;mitogen-activated protein kinase 1;protein tyrosine kinase ERK2.

Immunogen :

HPLC purified murine recombinant MAP Kinase. Clone 1B3B9

Specificity :

This antibody recognizes MAP kinase encoded by the mapk gene, Mr 42 kDa.

Package Size :

200 µg

Uses :

Immunoprecipitation;Western Blotting

Storage :

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.