PI3 Kinase b Antibody, p110b, clone 8C3.2 | EMD Millipore 05-1558 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PI3 Kinase b Antibody, p110b, clone 8C3.2

catalog :

05-1558

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8C3.2

reactivity :

human, mouse

application :

western blot, immunocytochemistry

product information

Catalog Number :

05-1558

Subcategory :

Cell Signaling

Product Name :

Anti-PI3 Kinase b Antibody, p110b, clone 8C3.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P42338

Host Name :

Mouse

Antigen :

PI3 Kinase b

Clone :

8C3.2

Conjugate :

Purified

Isotype :

IgMκ

Product Description :

Anti-PI3 Kinase b Antibody, p110b, clone 8C3.2

Cross Reactivity :

Rat;Human;Mouse

Background :

PI3 Kinase (Phosphatidylinositol 3-Kinase) is responsible for phosphorylation of the 3 position of the inositol ring of PI(4,5)P2, to generate PI(3,4,5)P3, a potent second messenger required for survival signaling, and insulin action. PI3 Kinase is a heterodimeric complex composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. Tyrosine phosphorylation of growth factor receptors creates docking sites for binding of p85 (through its SH2 domains) on the receptors; p85 brings with it p110, which is then proximal to its phospho-lipid substrate on the membrane. PI3 Kinase is also activated by Ras, and by the β:γ subunits of heterotrimeric G-proteins. PI3 Kinase is inhibitable by wortmannin, a useful tool for the study of the PI3 Kinase signaling pathway.

ALT Names :

PI3-kinase p110 subunit beta;PtdIns-3-kinase p110;phosphatidylinositol 3-kinase, catalytic, beta polypeptide;phosphoinositide-3-kinase, catalytic, beta polypeptide;PI3K beta;PI3 K beta;PI3 kinase b

Immunogen :

KLH-conjugated linear peptide corresponding to the N-terminus of human PI3 Kinase b.

Specificity :

This antibody recognizes PI3 Kinase b at the N-terminus.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt