Gemin3 Antibody, clone 12H12 | EMD Millipore 05-1533 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Gemin3 Antibody, clone 12H12

catalog :

05-1533

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

12H12

The same clone is also sold as:

Abcam: ab10305
BioLegend: 865503, 865501, 865502, 865504
Santa Cruz Biotechnology: sc-57007
LifeSpan Biosciences: LS-C82218, LS-C82260
Invitrogen: MA1-5779
ImmuQuest: IQ261, IQ204

reactivity :

human

application :

western blot

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1a	Gribling Burrer A, Leichter M, Wurth L, Huttin A, Schlotter F, Troffer Charlier N, et al. SECIS-binding protein 2 interacts with the SMN complex and the methylosome for selenoprotein mRNP assembly and translation. Nucleic Acids Res. 2017;45:5399-5413 pubmed publisher
	Kirino Y, Kim N, De Planell Saguer M, Khandros E, Chiorean S, Klein P, et al. Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability. Nat Cell Biol. 2009;11:652-8 pubmed publisher

product information

Catalog Number :

05-1533

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Gemin3 Antibody, clone 12H12

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9UHI6

Host Name :

Mouse

Antigen :

Gemin3

Clone :

12H12

Conjugate :

Purified

Product Description :

Anti-Gemin3 Antibody, clone 12H12

Cross Reactivity :

Human

Background :

Gemin3 is a member of the DEAD box protein family. The members of this family are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD). Some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Gemin 3 is a component of the survival of motor neurons (SMN) complex and codes for a DEAD box protein with an ATPase activity The SMN complex is essential for the biogenesis of spliceosomal small nuclear ribonucleoproteins and likely functions in the assembly, metabolism, and transport of a diverse number of other ribonucleoproteins. Specifically, the SMN complex assembles 7 Sm proteins (Gemin2-8) into a core structure around a highly conserved sequence of ribonucleic acid (RNA) found in small nuclear RNAs. The complex recognizes specific sequences and structural features of small nuclear RNAs and Sm proteins and assembles small nuclear ribonucleoproteins in a stepwise fashion.

ALT Names :

Component of gems 3;DEAD (Asp-Glu-Ala-Asp) box polypeptide 20;DEAD box protein 20;DEAD box protein DP 103;DEAD-box protein DP103;DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20, 103kD;SMN-interacting protein

Immunogen :

Recombinant protein corresponding to human Gemin-3.

Specificity :

This antibody recognizes Gemin-3.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt