This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
SMN Antibody, clone 2B1
catalog :
05-1532
quantity :
100 μg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2B1

The same clone is also sold as:
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation
product information
Catalog Number :
05-1532
Subcategory :
Epigenetics & Nuclear Function
Product Name :
Anti-SMN Antibody, clone 2B1
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
Q16637
Host Name :
Mouse
Antigen :
SMN
Clone :
2B1
Conjugate :
Purified
Isotype :
IgG1κ
Product Description :
Anti-SMN Antibody, clone 2B1
Cross Reactivity :
Human;Mouse;Xenopus
Background :
The survival of motor neurons (SMN) protein is essential for the biogenesis of small nuclear RNA (snRNA)-ribonucleoproteins (snRNPs), the major components of the pre-mRNA splicing machinery. Though it is ubiquitously expressed, SMN deficiency causes the motor neuron degenerative disease spinal muscular atrophy (SMA). SMN deficiency has unexpected cell type-specific effects on the repertoire of snRNAs and mRNAs. It alters the stoichiometry of snRNAs and causes widespread pre-mRNA splicing defects in numerous transcripts of diverse genes, preferentially those containing a large number of introns, in SMN-deficient mouse tissues. The SMN complex plays a role in RNA metabolism and in splicing regulation.
ALT Names :
Component of gems 1;gemin 1;spinal muscular atrophy (Werdnig-Hoffmann disease, Kugelberg-Welander disease);survival of motor neuron 1, telomeric
Immunogen :
His-tagged recombinant protein corresponding to human SMN.
Specificity :
This antibody recognizes SMN.
Package Size :
100 μg
Uses :
Western Blotting;Immunocytochemistry;Immunoprecipitation
Storage :
Stable for 1 year at 2-8°C from date of receipt
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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