Y14 Antibody, clone 4C4 | EMD Millipore 05-1511 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Y14 Antibody, clone 4C4

catalog :

05-1511

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4C4

The same clone is also sold as:

ImmuQuest: IQ275, IQ220
Abcam: ab5828
Santa Cruz Biotechnology: sc-32312
LifeSpan Biosciences: LS-C82232
MilliporeSigma: Y1253
Invitrogen: MA5-36288
Abnova: MAB2484

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 1

Reference
Zhang Y, Sachs M. Control of mRNA Stability in Fungi by NMD, EJC and CBC Factors Through 3'UTR Introns. Genetics. 2015;200:1133-48 pubmed publisher

product information

Catalog Number :

05-1511

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Y14 Antibody, clone 4C4

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9Y5S9

Host Name :

Mouse

Antigen :

Y14

Clone :

4C4

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-Y14 Antibody, clone 4C4

Cross Reactivity :

Human;Rat;Mouse

Background :

Y14 (RNA binding motif protein 8A or RBM8A), an RNA-binding protein, contains a conserved RNA-binding motif. Y14 is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.

ALT Names :

Binder of OVCA1-1;RNA binding motif protein 8A;RNA binding motif protein 8B;RNA-binding motif protein 8A;RNA-binding protein Y14;Ribonucleoprotein RBM8A;ribonucleoprotein RBM8

Immunogen :

Purified human Y14.

Specificity :

This antibody recognizes Y14.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry;Immunoprecipitation

Storage :

Stable for 1 year at 2-8°C from date of receipt