14-3-3 Antibody, 33 kDa isoforms, clone 8C3 | EMD Millipore 05-1425 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

14-3-3 Antibody, 33 kDa isoforms, clone 8C3

catalog :

05-1425

quantity :

500 μL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8C3

The same clone is also sold as:

Santa Cruz Biotechnology: sc-23957

reactivity :

human

application :

western blot

product information

Catalog Number :

05-1425

Subcategory :

Cell Signaling

Product Name :

Anti-14-3-3 Antibody, 33 kDa isoforms, clone 8C3

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P62258

Host Name :

Mouse

Antigen :

14-3-3

Clone :

8C3

Conjugate :

Ascites

Isotype :

IgG2a

Product Description :

Anti-14-3-3 Antibody, 33 kDa isoforms, clone 8C3

Cross Reactivity :

Rat;Sheep;Human

Background :

Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers, thus rendering 14-3-3 as a key multifunctional regulatory molecule. 14-3-3 isomers have been implicated in several neurological disorders: for example isoforms gamma, epsilon and beta are expressed in the cerebrospinal fluid of Creutzfeldt-Jakob patients, but not patients suffering from other neurological conditions such as Alzheimer's.

ALT Names :

14-3-3 epsilon;14-3-3 protein epsilon;mitochondrial import stimulation factor L subunit;protein kinase C inhibitor protein-1;tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation;protein, epsilon polypeptide;tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide 2

Immunogen :

Directed against a synthetic peptide corresponding to rat 14-3-3 epsilon, amino acids 208-244.

Specificity :

Clone 8C3 is specific for the 33 kDa epsilon isoform of 14-3-3 proteins and does not cross react with the 30 kDa 14-3-3 isoforms

Package Size :

500 μL

Uses :

Western Blotting

Storage :

Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.