Endoglin Antibody, clone P3D1 | EMD Millipore 05-1424 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Endoglin Antibody, clone P3D1

catalog :

05-1424

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

P3D1

The same clone is also sold as:

Developmental Studies Hybridoma Bank: P3D1
Santa Cruz Biotechnology: sc-18838

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1 ug/ml; loading ...; fig 2a	Aldabbous L, Abdul Salam V, McKinnon T, Duluc L, Pepke Zaba J, Southwood M, et al. Neutrophil Extracellular Traps Promote Angiogenesis: Evidence From Vascular Pathology in Pulmonary Hypertension. Arterioscler Thromb Vasc Biol. 2016;36:2078-87 pubmed publisher
immunohistochemistry - paraffin section; human; 1:1000; fig 5	Tao Y, Hu K, Tan F, Zhang S, Zhou M, Luo J, et al. SH3-domain binding protein 1 in the tumor microenvironment promotes hepatocellular carcinoma metastasis through WAVE2 pathway. Oncotarget. 2016;7:18356-70 pubmed publisher
	Detela G, Bain O, Kim H, Williams D, Mason C, Mathur A, et al. Donor Variability in Growth Kinetics of Healthy hMSCs Using Manual Processing: Considerations for Manufacture of Cell Therapies. Biotechnol J. 2018;13: pubmed publisher
	Sureshbabu A, Syed M, Boddupalli C, Dhodapkar M, Homer R, Minoo P, et al. Conditional overexpression of TGFÎ²1 promotes pulmonary inflammation, apoptosis and mortality via TGFÎ²R2 in the developing mouse lung. Respir Res. 2015;16:4 pubmed publisher
	Li M, Liu J, Wang S, Xu H, Cui L, Lv S, et al. Multipotent neural crest stem cell-like cells from rat vibrissa dermal papilla induce neuronal differentiation of PC12 cells. Biomed Res Int. 2014;2014:186239 pubmed publisher
	Valenzuela N, Mulder A, Reed E. HLA class I antibodies trigger increased adherence of monocytes to endothelial cells by eliciting an increase in endothelial P-selectin and, depending on subclass, by engaging Fc?Rs. J Immunol. 2013;190:6635-50 pubmed publisher
	Takehara Y, Yabuuchi A, Ezoe K, Kuroda T, Yamadera R, Sano C, et al. The restorative effects of adipose-derived mesenchymal stem cells on damaged ovarian function. Lab Invest. 2013;93:181-93 pubmed publisher
	Walsh E, Kim R, Del Valle L, Weaver M, Sheffield J, Lazarovici P, et al. Importance of interaction between nerve growth factor and ?9?1 integrin in glial tumor angiogenesis. Neuro Oncol. 2012;14:890-901 pubmed publisher
	Ji H, Zhao G, Luo J, Zhao X, Zhang M. Taurine postponed the replicative senescence of rat bone marrow-derived multipotent stromal cells in vitro. Mol Cell Biochem. 2012;366:259-67 pubmed publisher
	Nandoe Tewarie R, Bossers K, Ritfeld G, Blits B, Grotenhuis J, Verhaagen J, et al. Early passage bone marrow stromal cells express genes involved in nervous system development supporting their relevance for neural repair. Restor Neurol Neurosci. 2011;29:187-201 pubmed publisher
	Schmitter T, Agerer F, Peterson L, Munzner P, Hauck C. Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens. J Exp Med. 2004;199:35-46 pubmed

product information

Catalog Number :

05-1424

Subcategory :

Cell Signaling

Product Name :

Anti-Endoglin Antibody, clone P3D1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P17813

Host Name :

Mouse

Antigen :

Endoglin

Clone :

P3D1

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-Endoglin Antibody, clone P3D1

Cross Reactivity :

Human;Mouse;Rat

Background :

Endoglin is a homodimeric integral membrane glycoprotein comprised of 95 kDa subunit. Endoglin is a component of the TGF-B receptor system that functions as an ancillary receptor influencing binding of the Transforming Growth Factor beta (TGF-β) family ligands to signaling receptors. Endoglin binds TGF-B1 and TGF-B3 with high affinity but does not bind TGF-B2. Endoglin is expressed by vascular endothelial cells and syncytiotrophoblasts of placenta and is weakly expressed by stromalfibroblasts. It is also expressed by U937 cells and activated macrophages. Endoglin expression is up regulated on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation.

ALT Names :

CD105;Ancillary TGF-beta Receptor

Immunogen :

Human resting umbilical vein endothelial cells.

Specificity :

Reacts with human endoglin.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry;Immunocytochemistry;Immunoprecipitation;Flow Cytometry;ELISA

Storage :

Stable at 2-8°C for up to 1 year from date of receipt.