CD45RA Antibody, Clone MEM 56 | EMD Millipore 05-1413 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CD45RA Antibody, Clone MEM 56

catalog :

05-1413

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MEM 56

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

citations: 2

Reference
Angelini A, Castellani C, Ravara B, Franzin C, Pozzobon M, Tavano R, et al. Stem-cell therapy in an experimental model of pulmonary hypertension and right heart failure: role of paracrine and neurohormonal milieu in the remodeling process. J Heart Lung Transplant. 2011;30:1281-93 pubmed publisher
Nandoe Tewarie R, Bossers K, Ritfeld G, Blits B, Grotenhuis J, Verhaagen J, et al. Early passage bone marrow stromal cells express genes involved in nervous system development supporting their relevance for neural repair. Restor Neurol Neurosci. 2011;29:187-201 pubmed publisher

product information

Catalog Number :

05-1413

Subcategory :

Cell Signaling

Product Name :

Anti-CD45RA Antibody, Clone MEM 56

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P08575

Host Name :

Mouse

Antigen :

CD45RA

Clone :

MEM 56

Conjugate :

Purified

Isotype :

IgG2b

Product Description :

Anti-CD45RA Antibody, Clone MEM 56

Cross Reactivity :

Human;Mouse;Rat

Background :

CD45 is a receptor-tyrosine phosphatase required for antigen-induced signaling in T-cells and B-cells; its substrates are unknown. Interestingly, it associates with several Src-family tyrosine kinases, which are inhibited by tyrosine phosphorylation in their c-termini, suggesting a mechanism for signaling by CD45.

ALT Names :

CD45 antigen;Leukocyte common antigen precursor;SCID due to PTPRC deficiency;T200 glycoprotein;T200 leukocyte common antigen;Human homolog of severe combined immunodeficiency due to PTPRC deficiency;Leukocyte-common antigen;Protein tyrosine phosphatase, receptor type, C;Protein tyrosine phosphatase, receptor type, c polypeptide

Specificity :

This antibody recognizes the 220 kDa molecular weight component of the leucocyte common antigen complex expressed on some CD4+ T lymphocytes, B lymphocytes and CD8+ lymphocytes. The CD45R+/CD4+ lymphocytes functionally exert suppressor/inducer activity in in vitro assay systems. Antigen distribution: B-cells (lg+) 95% T-cells (E+) 70 + 10% Peripheral blood lymphocytes 68 + 8% T-cells (CD4+) 50 + 10% Monocytes 50 + 20% Thymocytes 5% Granulocytes 1%

Package Size :

100 µg

Uses :

Flow Cytometry;Immunofluorescence;Immunohistochemistry (Paraffin);Immunoprecipitation;Western Blotting

Storage :

For use within 1 month of date of purchase store at 2-8°C, for long term storage aliquot antibody into small volumes and store at -20°C for up to 1 year from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.