acetyl Histone H4 (Lys5/8/12/16) Antibody, clone 3HH4-4C10 | EMD Millipore 05-1355 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

acetyl Histone H4 (Lys5/8/12/16) Antibody, clone 3HH4-4C10

catalog :

05-1355

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3HH4-4C10

The same clone is also sold as:

Invitrogen: MA3-058

reactivity :

human, mouse

application :

western blot, immunocytochemistry

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 1a	Yu F, Shi G, Cheng S, Chen J, Wu S, Wang Z, et al. SUMO suppresses and MYC amplifies transcription globally by regulating CDK9 sumoylation. Cell Res. 2018;28:670-685 pubmed publisher
western blot; mouse; loading ...; fig 2a	Mathewson N, Jenq R, Mathew A, Koenigsknecht M, Hanash A, Toubai T, et al. Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease. Nat Immunol. 2016;17:505-513 pubmed publisher
immunocytochemistry; mouse; fig 1,2,3,4 western blot; mouse; fig 1,2,3,4	Bryant J, Donahue G, Wang X, Meyer Ficca M, Luense L, Weller A, et al. Characterization of BRD4 during mammalian postmeiotic sperm development. Mol Cell Biol. 2015;35:1433-48 pubmed publisher

product information

Catalog Number :

05-1355

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-acetyl Histone H4 (Lys5/8/12/16) Antibody, clone 3HH4-4C10

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P62805

Host Name :

Mouse

Antigen :

acetyl Histone H4 (Lys5/8/12/16)

Clone :

3HH4-4C10

Conjugate :

Ascites

Isotype :

IgG1κ

Product Description :

Anti-acetyl Histone H4 (Lys5/8/12/16) Antibody, clone 3HH4-4C10

Cross Reactivity :

Human;Mouse;Rat

Background :

Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Acetylation of histone H4 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs). Posttranslational acetylation of the conserved core histone N-terminal tail domains is typically associated with gene activation.

ALT Names :

H4KAc;Histone H4 (acetyl);H4 histone family, member N;H4 histone, family 2;histone 2, H4;histone 2, H4a;histone IV, family 2;histone cluster 2, H4a

Immunogen :

Linear peptide corresponding to human Histone H4 acetylated at Lys5/8/12/16.

Specificity :

This antibody recognizes Histone H4.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.