Histone H3 Antibody (Dimethyl K9, Phospho S10), clone 6HH3-2C5 | EMD Millipore 05-1354 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Histone H3 Antibody (Dimethyl K9, Phospho S10), clone 6HH3-2C5

catalog :

05-1354

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6HH3-2C5

The same clone is also sold as:

Invitrogen: MA3-064

reactivity :

human

application :

western blot, immunocytochemistry

citations: 1

Reference
Wang C, Li Y, Cai W, Bao X, Girton J, Johansen J, et al. Histone H3S10 phosphorylation by the JIL-1 kinase in pericentric heterochromatin and on the fourth chromosome creates a composite H3S10phK9me2 epigenetic mark. Chromosoma. 2014;123:273-80 pubmed publisher

product information

Catalog Number :

05-1354

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Histone H3 Antibody (Dimethyl K9, Phospho S10), clone 6HH3-2C5

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

B4E380

Host Name :

Mouse

Antigen :

Histone H3 (Dimethyl K9

Conjugate :

Ascites

Isotype :

IgG1κ

Product Description :

Anti-Histone H3 Antibody (Dimethyl K9, Phospho S10), clone 6HH3-2C5

Cross Reactivity :

Human;Drosophila

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. The term "Histone H3" alone is purposely ambiguous in that it does not distinguish between sequence variants or modification state. Histone H3 is an important protein in the emerging field of epigenetics, where its sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes.

ALT Names :

H3K9me2S10P;Histone H3 (di methyl K9, phospho S10);H3 histone, family 3B (H3.3B)

Immunogen :

Synthetic linear peptide corresponding to dimethyl (Lys9) and Phospho (Ser10) of Histone H3.

Specificity :

Antibody recognizes dimethyl (Lys9) phospho(Ser10) on Histone H3.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.