phospho-Histone H1 Antibody, clone 12D11 | EMD Millipore 05-1324 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho-Histone H1 Antibody, clone 12D11

catalog :

05-1324

quantity :

200 μL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

12D11

reactivity :

human, mouse, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 2

Reference
Li Y, Tong K, Lu J, Lin J, Li Z, Sang Y, et al. PRMT5-TRIM21 interaction regulates the senescence of osteosarcoma cells by targeting the TXNIP/p21 axis. Aging (Albany NY). 2020;12:2507-2529 pubmed publisher
Bury M, Le Calve B, Lessard F, Dal Maso T, Saliba J, Michiels C, et al. NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor. Cell Rep. 2019;29:1469-1481.e9 pubmed publisher

product information

Catalog Number :

05-1324

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-phospho-Histone H1 Antibody, clone 12D11

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P16401

Host Name :

Mouse

Antigen :

phospho-Histone H1

Clone :

12D11

Conjugate :

Culture Supernatant

Isotype :

IgMκ

Product Description :

Anti-phospho-Histone H1 Antibody, clone 12D11

Cross Reactivity :

Human;Bovine;Mouse;Vertebrates

Background :

Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into 30nm chromatin fibers and higher order structures.

ALT Names :

H1 histone family, member 5 ;Histone H1a ;histone 1, H1b;histone cluster 1, H1b

Immunogen :

The immunogen was KLH-conjugated bovine nuclear extract.

Specificity :

Recognizes phosphorylated Histone H1, Mr 32 kDa.

Package Size :

200 μL

Uses :

Immunohistochemistry;Immunocytochemistry;Immunoprecipitation;Western Blotting

Storage :

Stable for 1 year at -20°C from date of receipt. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.