phospho (Ser10) acetyl (Lys14) Histone H3 Antibody, clone 10H10.2 | EMD Millipore 05-1315 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho (Ser10) acetyl (Lys14) Histone H3 Antibody, clone 10H10.2

catalog :

05-1315

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10H10.2

reactivity :

human

application :

western blot

product information

Catalog Number :

05-1315

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-phospho (Ser10) acetyl (Lys14) Histone H3 Antibody, clone 10H10.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P84243

Host Name :

Mouse

Antigen :

phospho (Ser10) acetyl (Lys14) Histone H3

Clone :

10H10.2

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-phospho (Ser10) acetyl (Lys14) Histone H3 Antibody, clone 10H10.2

Cross Reactivity :

Human

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. The dual modification of histone H3 phosphorylated at serine 10 and acetylated at lysine 14 has been found at genomic sites with active transcription.

ALT Names :

H3S10PK14Ac;Histone H3 (phospho S10, acetyl K14);H3 histone family, member T;histone 3, H3;histone cluster 3, H3

Immunogen :

KLH-conjugated linear peptide corresponding to Histone H3 phosphorylated at Ser10 and acetylated at Lys14.

Specificity :

This antibody recognizes Histone H3 phosphorylated at Ser10 and acetylated at Lys14.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt