O-GlcNAc Antibody, clone 18B10.C7(3) | EMD Millipore 05-1244 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

O-GlcNAc Antibody, clone 18B10.C7(3)

catalog :

05-1244

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

18B10.C7

The same clone is also sold as:

Invitrogen: MA1-038

reactivity :

human, mouse

application :

western blot

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human	Reeves R, Lee A, Henry R, Zachara N. Characterization of the specificity of O-GlcNAc reactive antibodies under conditions of starvation and stress. Anal Biochem. 2014;457:8-18 pubmed publisher
western blot; mouse; fig s3	Borghgraef P, Menuet C, Theunis C, Louis J, Devijver H, Maurin H, et al. Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice. PLoS ONE. 2013;8:e84442 pubmed publisher
	Yao D, Xu L, Xu O, Li R, Chen M, Shen H, et al. O-Linked ?-N-Acetylglucosamine Modification of A20 Enhances the Inhibition of NF-?B (Nuclear Factor-?B) Activation and Elicits Vascular Protection After Acute Endoluminal Arterial Injury. Arterioscler Thromb Vasc Biol. 2018;38:1309-1320 pubmed publisher
	Xing D, Gong K, Feng W, Nozell S, Chen Y, Chatham J, et al. O-GlcNAc modification of NF?B p65 inhibits TNF-?-induced inflammatory mediator expression in rat aortic smooth muscle cells. PLoS ONE. 2011;6:e24021 pubmed publisher

product information

Catalog Number :

05-1244

Subcategory :

Cell Signaling

Product Name :

Anti-O-GlcNAc Antibody, clone 18B10.C7(3)

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O15294

Host Name :

Mouse

Antigen :

O-GlcNAc

Clone :

18B10.C7

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-O-GlcNAc Antibody, clone 18B10.C7(3)

Cross Reactivity :

Human

Background :

O-linked N-acetylglucosamine (O-GlcNAc), is a member of the O-GlcNAc transferase family. O-GlcNAc is a posttranslational modification characterized by the attachment of N-acetylglucosamine to specific serine/threonine hydroxyl groups. It plays an important role in nutrient sensing, gene expression, and protein degradation. O-GlcNAc is widely expressed in the pancreas and is present in smaller amounts in skeletal muscle, heart, brain and placenta.

ALT Names :

O-GlcNAc transferase p110 subunit;O-GlcNAc transferase subunit p110;O-linked GlcNAc transferase;O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase);O-linked N-acetylglucosamine transferase 110 kDa subunit;uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase

Immunogen :

SANM-conjugated linear peptide corresponding to human O-GluNAc.

Specificity :

This antibody recognizes O-GluNAc.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt