FGF-2/basic FGF Antibody, clone bFM-2 | EMD Millipore 05-118 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

FGF-2/basic FGF Antibody, clone bFM-2

catalog :

05-118

quantity :

500 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

bFM-2

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, radioimmunoassay, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section

citations: 15

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; rat; 1:250; fig 1b	Collazos Castro J, GarcÃa Rama C, Alves Sampaio A. Glial progenitor cell migration promotes CNS axon growth on functionalized electroconducting microfibers. Acta Biomater. 2016;35:42-56 pubmed publisher
immunohistochemistry - paraffin section; rat; 1:500; fig 4	Chidlow G, Wood J, Knoops B, Casson R. Expression and distribution of peroxiredoxins in the retina and optic nerve. Brain Struct Funct. 2016;221:3903-3925 pubmed
immunohistochemistry - frozen section; mouse western blot; mouse	Coorey N, Shen W, Zhu L, Gillies M. Differential Expression of IL-6/gp130 Cytokines, Jak-STAT Signaling and Neuroprotection After MÃ¼ller Cell Ablation in a Transgenic Mouse Model. Invest Ophthalmol Vis Sci. 2015;56:2151-61 pubmed publisher
western blot; mouse; 1:200 western blot; human	Santiago J, McNaughton L, Koleini N, Ma X, Bestvater B, Nickel B, et al. High molecular weight fibroblast growth factor-2 in the human heart is a potential target for prevention of cardiac remodeling. PLoS ONE. 2014;9:e97281 pubmed publisher
immunohistochemistry - free floating section; rat; 1:500	Effenberg A, Klein A, Gibb R, Carroll C, Baumgartner W, Grothe C, et al. Adult hemiparkinsonian rats do not benefit from tactile stimulation. Behav Brain Res. 2014;261:97-105 pubmed publisher
immunocytochemistry; bovine; 1:50 immunohistochemistry; bovine; 1:600 western blot; bovine; 1:600	Fátima L, Evangelista M, Silva R, Cardoso A, Baruselli P, Papa P. FSH up-regulates angiogenic factors in luteal cells of buffaloes. Domest Anim Endocrinol. 2013;45:224-37 pubmed publisher
western blot; human; fig 1i	Sáinz Jaspeado M, Huertas Martínez J, Lagares Tena L, Martín Liberal J, Mateo Lozano S, de Alava E, et al. EphA2-induced angiogenesis in ewing sarcoma cells works through bFGF production and is dependent on caveolin-1. PLoS ONE. 2013;8:e71449 pubmed publisher
immunohistochemistry - frozen section; rat; 1:1000 western blot; rat; 1:500	Tripathi R, McTigue D. Chronically increased ciliary neurotrophic factor and fibroblast growth factor-2 expression after spinal contusion in rats. J Comp Neurol. 2008;510:129-44 pubmed publisher
	Shibeeb O, Wood J, Casson R, Chidlow G. Effects of a conventional photocoagulator and a 3-ns pulse laser on preconditioning responses and retinal ganglion cell survival after optic nerve crush. Exp Eye Res. 2014;127:77-90 pubmed publisher
	Zhao H, Heusler E, Jones G, Li L, Werner V, Germershaus O, et al. Decoration of silk fibroin by click chemistry for biomedical application. J Struct Biol. 2014;186:420-30 pubmed publisher
	Do M, Suzuki T, Gerelt B, Sato Y, Mizunoya W, Nakamura M, et al. Time-coordinated prevalence of extracellular HGF, FGF2 and TGF-?3 in crush-injured skeletal muscle. Anim Sci J. 2012;83:712-7 pubmed publisher
	Waisberg D, Parra E, Barbas Filho J, Fernezlian S, Capelozzi V. Increased fibroblast telomerase expression precedes myofibroblast α-smooth muscle actin expression in idiopathic pulmonary fibrosis. Clinics (Sao Paulo). 2012;67:1039-46 pubmed
	Santiago J, Ma X, McNaughton L, Nickel B, Bestvater B, Yu L, et al. Preferential accumulation and export of high molecular weight FGF-2 by rat cardiac non-myocytes. Cardiovasc Res. 2011;89:139-47 pubmed publisher
	Kirwin S, Kanaly S, Linke N, Edelman J. Strain-dependent increases in retinal inflammatory proteins and photoreceptor FGF-2 expression in streptozotocin-induced diabetic rats. Invest Ophthalmol Vis Sci. 2009;50:5396-404 pubmed publisher
	Julien S, Kreppel F, Beck S, Heiduschka P, Brito V, Schnichels S, et al. A reproducible and quantifiable model of choroidal neovascularization induced by VEGF A165 after subretinal adenoviral gene transfer in the rabbit. Mol Vis. 2008;14:1358-72 pubmed

product information

Catalog Number :

05-118

Subcategory :

Cell Signaling

Product Name :

Anti-FGF-2/basic FGF Antibody, clone bFM-2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P09038

Host Name :

Mouse

Antigen :

FGF-2/basic FGF

Clone :

bFM-2

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-FGF-2/basic FGF Antibody, clone bFM-2

Cross Reactivity :

Human;Bovine;Mouse;Rat

Background :

FGF basic (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF2 mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

ALT Names :

Basic fibroblast growth factor;basic fibroblast growth factor bFGF;fibroblast growth factor 2;fibroblast growth factor 2 (basic);heparin-binding growth factor 2

Immunogen :

Purified bovine brain basic FGF (FGF-2, HBGF-2). Clone bFM-2.

Specificity :

This antibody detects FGF-2/basic FGF.

Package Size :

500 µg

Uses :

Immunohistochemistry;Radioimmunoassay;Western Blotting

Storage :

Stable for 1 year at -20ºC from date of receipt.