Focal Adhesion Kinase Antibody, clone BLAb2H7 | EMD Millipore 05-1139 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Focal Adhesion Kinase Antibody, clone BLAb2H7

catalog :

05-1139

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

BLAb2H7

reactivity :

human, mouse, chicken

application :

western blot, immunohistochemistry, immunoprecipitation

product information

Catalog Number :

05-1139

Subcategory :

Cell Structure

Product Name :

Anti-Focal Adhesion Kinase Antibody, clone BLAb2H7

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q05397

Host Name :

Mouse

Antigen :

Focal Adhesion Kinase

Clone :

BLAb2H7

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Focal Adhesion Kinase Antibody, clone BLAb2H7

Cross Reactivity :

Human;Mouse;Rat;Chicken

Background :

FAK is a 125 Kd protein that is recruited as a participant in focal adhesion dynamics between cells and has a role in motility and cell survival. FAK is a highly conserved, non-receptor tyrosine kinase originally identified as a substrate for the oncogene protein tyrosine kinase v-src (Guan, J L and Shalloway, D). This cytosolic kinase has been implicated in diverse cellular roles including cell locomotion, mitogen response and cell survival. FAK is typically located at structures known as focal adhesions, these are multi-protein structures that link the extracellular matrix (ECM) to the cytoplasmic cytoskeleton. Additional components of focal adhesions include actin, filamin, vinculin, talin, paxillin and tensin (Burridge, K, et al).

ALT Names :

FADK 1;PTK2 protein tyrosine kinase 2;Protein-tyrosine kinase 2;focal adhesion kinase 1

Immunogen :

Recombinant fragment derived from the amino terminal region of chicken FAK, amino acid residues 103 to 553.

Specificity :

This antibody recognizes Focal Adhesion Kinase

Package Size :

100 μg

Uses :

Western Blotting;Immunoprecipitation

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.