STAT3 Antibody, clone 18F7.1 | EMD Millipore 05-1078 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

STAT3 Antibody, clone 18F7.1

catalog :

05-1078

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

18F7.1

reactivity :

human, mouse

application :

western blot, immunocytochemistry

product information

Catalog Number :

05-1078

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-STAT3 Antibody, clone 18F7.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P40763

Host Name :

Mouse

Antigen :

STAT3

Clone :

18F7.1

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-STAT3 Antibody, clone 18F7.1

Cross Reactivity :

Human;Mouse

Background :

STAT proteins (Signal Transduction and Activators of Transcription) are latent cytoplasmic transcription factors that have the dual function of signal transduction and activation of transcription. STATs are activated by tyrosine phosphorylation in response to different ligands, after which they translocate to the cell nucleus. The N-terminal region is highly homologous among the STAT proteins and surrounds a completely conserved arginine residue. STATs are a part of the JAK-STAT signaling pathway – a major pathway of the immune system. All cytokines transduce critical signals through this pathway. STAT3 has been shown to be activated by IFN alpha but not IFN beta. The transcription factors associated with STAT3 are c-Jun and cyclic AMP responsive enhancer binding protein (CREB). Deletion of the STAT3 gene in knock out mice was lethal at the early embryonic stage.

ALT Names :

Acute-phase response factor DNA-binding protein APRF signal transducer and activator of transcription 3 signal transducer and activator of transcription 3 (acute-phase response factor)

Immunogen :

KLH-conjugated linear peptide corresponding to human STAT3.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt