Phospho-Stat1 (Tyr701) Antibody, clone 5C9.2 | EMD Millipore 05-1064 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Phospho-Stat1 (Tyr701) Antibody, clone 5C9.2

catalog :

05-1064

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5C9.2

reactivity :

human, mouse

application :

western blot

product information

Catalog Number :

05-1064

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Phospho-Stat1 (Tyr701) Antibody, clone 5C9.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P42224

Host Name :

Mouse

Antigen :

Phospho-Stat1 (Tyr701)

Clone :

5C9.2

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Phospho-Stat1 (Tyr701) Antibody, clone 5C9.2

Cross Reactivity :

Human;Mouse;Rat

Background :

STATs (Signal-Transducing Activators of Transcription) are the principle substrates of JAK kinases, and mediators of cytokine signaling. STAT proteins have SH2 domains, and once phosphorylated by JAK kinases, STATs dimerize in a head-to-tail fashion, through their SH2 domains. STAT1 is a critical mediator of IFN signaling, STAT4 is specific to IL-12, STAT6 is activated primarily by IL-4 and IL-13, while STAT5 A and B appear to be most important to the function of growth hormone and prolactin. STAT3 is involved in multiple signaling pathways, and mice deficient in it are not viable. In addition to tyrosine phosphorylation, many STAT proteins are targets of Ser/Thr kinases, and those phosphorylation events potentiate STAT-induced transcription. The phosphorylation state of STATs can be monitored by phosphorylation state-specific antibodies.

ALT Names :

Transcription factor ISGF-3 components p91/p84;signal transducer and activator of transcription 1

Immunogen :

KLH-conjugated linear peptide corresponding to the region around phosphorylated tyrosine 701.

Specificity :

This antibody recognizes phosphorylated STAT1 at tyrosine 701.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8ºC from date of receipt.