This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Interleukin 4 (IL-4) Antibody, clone 11.B.11
catalog :
04-964
quantity :
100 μg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
reactivity :
mouse
application :
flow cytometry
citations: 6
Reference
Puleston D, Buck M, Klein Geltink R, Kyle R, Caputa G, O Sullivan D, et al. Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation. Cell Metab. 2019;: pubmed publisher
Booth A, Grabauskiene S, Wood S, Lu G, Burrell B, Bishop D. IL-6 promotes cardiac graft rejection mediated by CD4+ cells. J Immunol. 2011;187:5764-71 pubmed publisher
Booth A, Wood S, Cornett A, Dreffs A, Lu G, Muro A, et al. Recipient-derived EDA fibronectin promotes cardiac allograft fibrosis. J Pathol. 2012;226:609-18 pubmed publisher
Witte H, Neukirchen D, Bradke F. Microtubule stabilization specifies initial neuronal polarization. J Cell Biol. 2008;180:619-32 pubmed publisher
Gessner A, Mohrs K, Mohrs M. Mast cells, basophils, and eosinophils acquire constitutive IL-4 and IL-13 transcripts during lineage differentiation that are sufficient for rapid cytokine production. J Immunol. 2005;174:1063-72 pubmed
Wu D, Segal N, Sidobre S, Kronenberg M, Chapman P. Cross-presentation of disialoganglioside GD3 to natural killer T cells. J Exp Med. 2003;198:173-81 pubmed
product information
Catalog Number :
04-964
Subcategory :
Inflammation & Immunology
Product Name :
Anti-Interleukin 4 (IL-4) Antibody, clone 11.B.11
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P07750
Host Name :
Rat
Antigen :
Interleukin 4 (IL-4)
Clone :
11B11
Conjugate :
Purified
Isotype :
IgG1κ
Product Description :
Anti-Interleukin 4 (IL-4) Antibody, clone 11.B.11
Cross Reactivity :
Mouse
Background :
Interleukin-4 (IL-4) is a cytokine that stimulates activated B-cell and T-cell proliferation and induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. These Th2 cells, in turn, also produce IL-4. IL-4 also acts as a key regulator in humoral and adaptive immunity and induces B-cell class switching to IgE, as well as up-regulating MHC class II production. Mutations in the IL-4 gene may lead to a susceptibility to ischemic stroke or cerebral infarction. Overproduction of IL-4 is associated with allergies.
ALT Names :
B cell growth factor 1;B-cell stimulatory factor 1;B_cell stimulatory factor 1;Lymphocyte stimulatory factor 1;interleukin 4
Immunogen :
Recombinant protein corresponding to mouse IL-4.
Specificity :
This antibody recognizes IL-4.
Package Size :
100 μg
Uses :
Flow Cytometry;Enzyme Assay
Storage :
Stable for 1 year at 2-8°C from date of receipt
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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