CTLA4 (CD152) Antibody, clone 9H10 | EMD Millipore 04-963 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CTLA4 (CD152) Antibody, clone 9H10

catalog :

04-963

quantity :

100 µg

clonality :

monoclonal

host :

hamsters

conjugate :

nonconjugated

clone name :

9H10

The same clone is also sold as:

Invitrogen: 16-1521-81, 16-1521-82, 16-1521-85, 16-1521-025, 16-1521-95, 16-1521-38, 16-1521-050
BioLegend: 106202, 106215, 106214, 106206, 106212, 106210, 106211, 106207, 106208, 106205, 106209, 106213, 106216
LifeSpan Biosciences: LS-C195552, LS-C350395, LS-C195553, LS-C14298, LS-C350401
OriGene: AM08061PU-N, AM08061LE-N
ichorbio: ICH1084, ICH1084UL
Abnova: MAB3241
Absolute Antibody: Ab00894-2.0, Ab00894-2.3, Ab00894-23.0, Ab00894-22.0, Ab00894-1.32
Bio X Cell: BE0131-1MG, BE0131-25MG, BE0131-5MG, BE0131-50MG, BP0131-100MG, BP0131-50MG, BE0131-100MG, BP0131-5MG, BP0131-25MG

reactivity :

mouse

application :

western blot, immunoprecipitation, flow cytometry

product information

Catalog Number :

04-963

Subcategory :

Inflammation & Immunology

Product Name :

Anti-CTLA4 (CD152) Antibody, clone 9H10

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P16410

Host Name :

Hamster

Antigen :

CTLA4 (CD152)

Clone :

9H10

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-CTLA4 (CD152) Antibody, clone 9H10

Cross Reactivity :

Mouse

Background :

CTLA4, Cytotoxic T lymphocyte antigen 4, also known as CD152, belongs to the family of immunoglobins. It is widely expressed on activated T lymphocytes and is involved in the maintenance of immune tolerance. CTLA4 is a homolog for CD28. They are able to bind to B7-1 and B7-2; however, CTLA4 is able to bind to both with a higher affinity. Defects in CTLA4 have been linked to Rheumatoid arthritis, Addisons disease, Graves disease and many other autoimmune diseases.

ALT Names :

CD152 antigen ;Cytotoxic T-lymphocyte-associated antigen 4 ;celiac disease 3;cytotoxic T-lymphocyte-associated protein 4;cytotoxic T-lymphocyte-associated serine esterase-4;ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4

Immunogen :

Mouse CTLA-4/human IgG1 fusion protein corresponding to residues surrounding CTLA4.

Specificity :

This antibody recognizes CTLA4. Antibody 9H10 is specific for CTLA-4 by four criteria: (a) Reactivity against CTLA-4 Ig but not CD4 lg; (b) the ability to block CTLA-4 Ig binding to B7 transfectants; (c) the ability to stain activated T cells but not freshly isolated T cells; and (d) the ability to stain a CTLA-4 transfectant but not control transfectants (Krummel, M.F., et al., 1995).

Package Size :

100 µg

Uses :

Western Blotting;Flow Cytometry;Immunoprecipitation

Storage :

Stable at 2-8°C for 1 year from date of receipt.