Beta Catenin Antibody, clone 7F7.2 | EMD Millipore 04-958 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Beta Catenin Antibody, clone 7F7.2

catalog :

04-958

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7F7.2

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - free floating section

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; rat; 1:200; loading ...; fig 6b immunohistochemistry - free floating section; mouse; 1:400; loading ...; fig 1a	Mecha M, Yanguas Casás N, Feliú A, Mestre L, Carrillo Salinas F, Riecken K, et al. Involvement of Wnt7a in the role of M2c microglia in neural stem cell oligodendrogenesis. J Neuroinflammation. 2020;17:88 pubmed publisher
western blot; mouse; 1:400; fig 3c	Li N, Liu S, Zhang H, Deng Z, Zhao H, Zhao Q, et al. Exogenous R-Spondin1 Induces Precocious Telogen-to-Anagen Transition in Mouse Hair Follicles. Int J Mol Sci. 2016;17: pubmed publisher

product information

Catalog Number :

04-958

Subcategory :

Cell Signaling

Product Name :

Anti-Beta Catenin Antibody, clone 7F7.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P35222

Host Name :

Mouse

Antigen :

Beta Catenin

Clone :

7F7.2

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Beta Catenin Antibody, clone 7F7.2

Cross Reactivity :

Human;Mouse;Rat

Background :

Catenins are proteins found in complexes with cadherin cell adhesion molecules of animal cells. The first two catenins that were identified became known as α-catenin and β-catenin. α-catenin can bind to β-catenin and can also bind actin. β-catenin binds the cytoplasmic domain of some cadherins. When β-catenin was sequenced it was found to be a member of the armadillo family of proteins. These proteins have multiple copies of the so-called armadillo repeat domain which is specialized for protein-protein binding. An increase in β-catenin production has been noted in those people who have Basal Cell Carcinoma and leads to the increase in proliferation of related tumors. When β-catenin is not associated with cadherins and α-catenin, it can interact with other proteins such as Catenin Beta Interacting Protein 1 (ICAT) and adenomatosis polyposis coli (APC). Recent evidence suggests that β-catenin plays an important role in various aspects of liver biology including liver development (both embryonic and postnatal), liver regeneration following partial hepatectomy, HGF-induced hepatpomegaly, liver zonation, and pathogenesis of liver cancer.

ALT Names :

Beta Catenin;Catenin (cadherin-associated protein), beta 1

Immunogen :

Full length, GST-tagged recombinant beta catenin.

Specificity :

This antibody recognizes beta catenin.

Package Size :

100 µg

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt